MYL2 and CDC42BPA

Number of citations of the paper that reports this interaction (PubMedID 9418861)
82

Data Source:
HPRD (in vitro)

		MYL2	CDC42BPA
Description		myosin light chain 2	CDC42 binding protein kinase alpha
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Actin Cytoskeleton Myosin Complex Myofibril Sarcomere A Band Cardiac Myofibril	Cytoplasm Cytoskeleton Cell-cell Junction Lamellipodium Cell Leading Edge Actomyosin Extracellular Exosome
	Molecular Function	Actin Monomer Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Regulation Of Striated Muscle Contraction Heart Development Post-embryonic Development Muscle Filament Sliding Negative Regulation Of Cell Growth Muscle Cell Fate Specification Muscle Fiber Development Cardiac Myofibril Assembly Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Positive Regulation Of The Force Of Heart Contraction	Protein Phosphorylation Cell Migration Peptidyl-threonine Phosphorylation Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction
Pathways		Striated Muscle Contraction
Drugs
Diseases		Hypertrophic cardiomyopathy (HCM)
GWAS		Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Alcohol consumption (max-drinks) ( 29460428) Body mass index ( 24861553) Coffee consumption ( 29367735) Coronary heart disease ( 23364394) Drinking behavior ( 23364009) Gamma glutamyl transpeptidase ( 21909109) Glycemic traits ( 23575436) Gout ( 25646370) HDL cholesterol ( 21909109) HDL cholesterol levels ( 28334899) High density lipoprotein cholesterol levels ( 30718733) Metabolic syndrome ( 25705158) Metabolic syndrome (multivariate analysis) ( 29632305) Neutrophil count ( 29403010) Urate levels ( 31578528) White blood cell count ( 29403010)	Blond vs. brown/black hair color ( 30531825) Blood urea nitrogen levels ( 31152163) Diastolic blood pressure ( 28135244) Macular thickness ( 30535121) Mercury levels ( 26025379) Myeloid white cell count ( 27863252) Optic cup area ( 25631615 31798171) Optic disc area ( 25631615 31798171 28073927) Optic disc size ( 31809533) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		11 interacting genes: CDC42BPA GJB5 LRSAM1 MYOC NHP2 PAK2 PKM PPP1R12C TRIM63 USP6 ZNF529	7 interacting genes: CDC42 LIMK1 LIMK2 MYL2 MYL9 PPM1A PPP1R12C
Entrez ID		4633	8476
HPRD ID		01181	04562
Ensembl ID		ENSG00000111245	ENSG00000143776
Uniprot IDs		P10916 Q6IB42	Q5VT25
PDB IDs		5TBY
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?