MYCN and GRSF1

Number of citations of the paper that reports this interaction (PubMedID 17967896)
61

Data Source:
BioGRID (unspecified method)

		MYCN	GRSF1
Description		MYCN proto-oncogene, bHLH transcription factor	G-rich RNA sequence binding factor 1
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GO Annotations	Cellular Component	Chromatin Nuclear Chromatin Nucleus Nucleoplasm Nucleolus	Cytoplasm Mitochondrion Ribonucleoprotein Granule Mitochondrial Nucleoid
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Kinase Binding Protein Dimerization Activity	RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA	Positive Regulation Of Mitochondrial RNA Catabolic Process MRNA Polyadenylation TRNA Processing Anterior/posterior Pattern Specification Morphogenesis Of Embryonic Epithelium
Pathways			Viral mRNA Translation
Drugs
Diseases		Neuroblastoma Feingold syndrome
GWAS		Asthma or chronic obstructive pulmonary disease ( 24993907) Basal cell carcinoma ( 25855136) Height ( 31562340) Metabolite levels ( 23823483) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft palate ( 31609978) Pulmonary function (smoking interaction) ( 23284291) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Wilms tumor ( 22544364)	Type 2 diabetes ( 30718926)
Interacting Genes		20 interacting genes: CSNK2A1 CSNK2A2 DOT1L EZH2 FBXW7 GRSF1 HUWE1 MAX MXD1 NEDD4 NMI NONO RUNX3 SIRT1 SP1 TRIM32 YAF2 YBX1 YEATS4 ZBTB17	2 interacting genes: MYCN PSMD10
Entrez ID		4613	2926
HPRD ID		01278	07276
Ensembl ID		ENSG00000134323	ENSG00000132463
Uniprot IDs		A0A1W2PPD9 P04198 Q9H224	A0A024RD99 Q12849
PDB IDs		5G1X	2LMI 4QU6 4QU7
Enriched GO Terms of Interacting Partners?
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