MYCN and YAF2

Number of citations of the paper that reports this interaction (PubMedID 11593398)
3

Data Source:
HPRD (in vitro, two hybrid)

		MYCN	YAF2
Description		MYCN proto-oncogene, bHLH transcription factor	YY1 associated factor 2
Image
GO Annotations	Cellular Component	Chromatin Nuclear Chromatin Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Kinase Binding Protein Dimerization Activity	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA	Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases		Neuroblastoma Feingold syndrome
GWAS		Asthma or chronic obstructive pulmonary disease ( 24993907) Basal cell carcinoma ( 25855136) Height ( 31562340) Metabolite levels ( 23823483) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft palate ( 31609978) Pulmonary function (smoking interaction) ( 23284291) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Wilms tumor ( 22544364)
Interacting Genes		20 interacting genes: CSNK2A1 CSNK2A2 DOT1L EZH2 FBXW7 GRSF1 HUWE1 MAX MXD1 NEDD4 NMI NONO RUNX3 SIRT1 SP1 TRIM32 YAF2 YBX1 YEATS4 ZBTB17	10 interacting genes: GABPB1 MYC MYCN NEDD8 SETBP1 TBK1 UBC XAGE1B YY1 ZFP42
Entrez ID		4613	10138
HPRD ID		01278	09606
Ensembl ID		ENSG00000134323	ENSG00000015153
Uniprot IDs		A0A1W2PPD9 P04198 Q9H224	B4DJQ9 G3V212 Q8IY57
PDB IDs		5G1X	2D9G
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?