MVD and HSPA9

Number of citations of the paper that reports this interaction (PubMedID 12646231)
17

Data Source:
HPRD (two hybrid, in vivo)

		MVD	HSPA9
Description		mevalonate diphosphate decarboxylase	heat shock protein family A (Hsp70) member 9
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GO Annotations	Cellular Component	Peroxisome Cytosol	Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome
	Molecular Function	Diphosphomevalonate Decarboxylase Activity ATP Binding Hsp70 Protein Binding Protein Homodimerization Activity	RNA Binding Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding ATPase Activity, Coupled Protein Binding Involved In Protein Folding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Dolichyl Diphosphate Biosynthetic Process Cholesterol Biosynthetic Process Positive Regulation Of Cell Proliferation Isoprenoid Biosynthetic Process Isopentenyl Diphosphate Biosynthetic Process, Mevalonate Pathway Regulation Of Cholesterol Biosynthetic Process	Protein Export From Nucleus Response To Unfolded Protein Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Interleukin-12-mediated Signaling Pathway Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP) Synthesis of Dolichyl-phosphate	Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Feeling fed-up ( 29500382) Hair color ( 26926045)	Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)
Interacting Genes		5 interacting genes: BTAF1 EEF1G EIF4EBP1 GNB5 HSPA9	22 interacting genes: APP DNAJC19 DNLZ FGF1 HSP90B1 HSPBP1 LSM8 MATK MVD NELFB PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG
Entrez ID		4597	3313
HPRD ID		04454	02770
Ensembl ID		ENSG00000167508	ENSG00000113013
Uniprot IDs		P53602	A0A384P5G6 P38646
PDB IDs		3D4J	3N8E 4KBO 6NHK 6P2U
Enriched GO Terms of Interacting Partners?
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