HSPA9 and HSPBP1

Number of citations of the paper that reports this interaction (PubMedID 19659607)
15

Data Source:
HPRD (in vitro)

		HSPA9	HSPBP1
Description		heat shock protein family A (Hsp70) member 9	HSPA (Hsp70) binding protein 1
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome	Cytoplasm Endoplasmic Reticulum
	Molecular Function	RNA Binding Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding ATPase Activity, Coupled Protein Binding Involved In Protein Folding Unfolded Protein Binding Misfolded Protein Binding	Adenyl-nucleotide Exchange Factor Activity Enzyme Inhibitor Activity Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Export From Nucleus Response To Unfolded Protein Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Interleukin-12-mediated Signaling Pathway Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation	Protein Folding Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catalytic Activity
Pathways		Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)
Interacting Genes		22 interacting genes: APP DNAJC19 DNLZ FGF1 HSP90B1 HSPBP1 LSM8 MATK MVD NELFB PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG	11 interacting genes: APP CLK1 HSPA1A HSPA1B HSPA2 HSPA4 HSPA5 HSPA8 HSPA9 LRIF1 NOTCH2NLA
Entrez ID		3313	23640
HPRD ID		02770	09991
Ensembl ID		ENSG00000113013	ENSG00000133265
Uniprot IDs		A0A384P5G6 P38646	Q9NZL4
PDB IDs		3N8E 4KBO 6NHK 6P2U	1XQR 1XQS
Enriched GO Terms of Interacting Partners?
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