MPZ and PMP22

Number of citations of the paper that reports this interaction (PubMedID 10212299)
18

Data Source:
HPRD (in vivo, in vitro)

		MPZ	PMP22
Description		myelin protein zero	peripheral myelin protein 22
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Myelin Sheath Synapse	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Compact Myelin Synapse
	Molecular Function	Structural Molecule Activity	Protein Binding
	Biological Process	Chemical Synaptic Transmission Myelination Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Aggregation	Chemical Synaptic Transmission Peripheral Nervous System Development Cell Death Negative Regulation Of Cell Proliferation Negative Regulation Of Neuron Projection Development Bleb Assembly Myelin Assembly Myelination
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination	EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy	Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Hip circumference adjusted for BMI ( 28552196) Visceral adipose tissue adjusted for BMI ( 22589738)	Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 29566793) Corneal structure ( 23291589) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)
Interacting Genes		3 interacting genes: PINX1 PMP22 PSMB3	8 interacting genes: CANX CREB3 DDX52 KLRC1 LMNA MPZ PEX19 SMIM3
Entrez ID		4359	5376
HPRD ID		01159	03059
Ensembl ID		ENSG00000158887	ENSG00000109099
Uniprot IDs		A0A5F9ZI26 P25189	A8MU75 Q01453 Q6FH25
PDB IDs		1N2P 3OAI
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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