PMP22 and DDX52

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PMP22	DDX52
Description		peripheral myelin protein 22	DExD-box helicase 52
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Compact Myelin Synapse	Nucleoplasm Nucleolus Membrane
	Molecular Function	Protein Binding	RNA Binding RNA Helicase Activity ATP Binding
	Biological Process	Chemical Synaptic Transmission Peripheral Nervous System Development Cell Death Negative Regulation Of Cell Proliferation Negative Regulation Of Neuron Projection Development Bleb Assembly Myelin Assembly Myelination	RRNA Processing Maturation Of SSU-rRNA
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 29566793) Corneal structure ( 23291589) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)	Ovarian cancer ( 23535730)
Interacting Genes		8 interacting genes: CANX CREB3 DDX52 KLRC1 LMNA MPZ PEX19 SMIM3	5 interacting genes: AP4M1 HLCS MTNR1A PMP22 UTP23
Entrez ID		5376	11056
HPRD ID		03059	09911
Ensembl ID		ENSG00000109099	ENSG00000278053
Uniprot IDs		A8MU75 Q01453 Q6FH25	B3KM65 Q9Y2R4
PDB IDs			3DKP
Enriched GO Terms of Interacting Partners?
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