MPP3 and RPS2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MPP3	RPS2
Description		membrane palmitoylated protein 3	ribosomal protein S2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding Fibroblast Growth Factor Binding Enzyme Binding Cadherin Binding
	Biological Process		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Positive Regulation Of Ubiquitin-protein Transferase Activity
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis RMTs methylate histone arginines rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Protein methylation Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Copper
Diseases
GWAS		HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068)	Atrial fibrillation ( 29892015)
Interacting Genes		35 interacting genes: APP ARL2BP CADM1 CCDC137 CRABP1 ERBIN EZR FAM171B FBXO7 GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A MCM2 MDH1 NOA1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TBK1 TIRAP TMEM37 TRAF2 TRIM41 ZPR1	19 interacting genes: ANXA2 ANXA7 CDKN1A DNM2 FBXO7 FGF1 FGF3 GABARAPL2 GADD45A GRB7 GSK3B MPP3 PRMT3 PTEN SMN1 SOX5 TK1 TRAF6 YWHAG
Entrez ID		4356	6187
HPRD ID		03069	04690
Ensembl ID		ENSG00000161647	ENSG00000140988
Uniprot IDs		D3DX46 Q13368	P15880
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6G18 6G4S 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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