MMP9 and COL4A1

  • Number of citations of the paper that reports this interaction (PubMedID 9878537)
  • 11
  • Data Source:
  • HPRD (in vivo)

MMP9

COL4A1

Description matrix metallopeptidase 9 collagen type IV alpha 1 chain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related nuclear cataracts ( 24951543)
  • Arterial stiffness ( 20031579)
  • Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833)
  • Coronary artery disease ( 29212778 24262325 30104761 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 21378990)
  • Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133)
  • Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136)
  • Intraocular pressure ( 29785010 31959993)
  • Lateral ventricle volume ( 31530798)
  • Metabolite levels ( 23823483)
  • Monocyte count ( 27863252)
  • Myocardial infarction ( 26343387)
  • Night sleep phenotypes ( 27126917)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Obesity-related traits ( 23251661)
  • Peripheral artery disease ( 31285632)
  • Pulse pressure ( 30578418)
  • Stroke ( 30383316 29531354)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes 31 interacting genes: AREG BTC CD44 COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 CXCL1 CXCL5 CXCL6 CXCL8 EPHB2 FN1 HAPLN1 KISS1 LCN2 MMP10 MMP26 MMP7 PLG PRSS2 PZP RECK TFPI THBS1 THBS2 TIMP3 27 interacting genes: ACHE APCS APP BMP3 CD93 COL4A2 COL7A1 DCN DISC1 FBLN2 FN1 HABP2 MAG MATN2 MMP9 NID1 NID2 OSM PDGFA PDGFB SAA1 SAA2 SAA4 SERPINE2 SMAD1 TGFBI THBS1
Entrez ID 4318 1282
HPRD ID 00387 00359
Ensembl ID ENSG00000100985 ENSG00000187498
Uniprot IDs P14780 A5PKV2 P02462
PDB IDs 1GKC 1GKD 1ITV 1L6J 1LKG 2OVX 2OVZ 2OW0 2OW1 2OW2 4H1Q 4H2E 4H3X 4H82 4HMA 4JIJ 4JQG 4WZV 4XCT 5CUH 5I12 5TH6 5TH9 5UE3 5UE4 6ESM 1LI1 5NAX 5NAY 6MPX
Enriched GO Terms of Interacting Partners?
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