RAB8A and BIRC6

Number of citations of the paper that reports this interaction (PubMedID 18329369)
73

Data Source:
HPRD (in vivo)

		RAB8A	BIRC6
Description		RAB8A, member RAS oncogene family	baculoviral IAP repeat containing 6
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GO Annotations	Cellular Component	Golgi Membrane Endosome Centrosome Centriole Cytosol Plasma Membrane Cilium Synaptic Vesicle Endomembrane System Postsynaptic Density Trans-Golgi Network Transport Vesicle Midbody Phagocytic Vesicle Membrane Trans-Golgi Network Membrane Ciliary Basal Body Neuronal Cell Body Dendritic Spine Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Ciliary Base Non-motile Cilium Glutamatergic Synapse	Spindle Pole Nucleus Endosome Trans-Golgi Network Microtubule Organizing Center Membrane Midbody Flemming Body
	Molecular Function	GTPase Activity Protein Binding GTP Binding Rab GTPase Binding GDP Binding Protein Kinase Binding Myosin V Binding	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Axonogenesis Protein Secretion Regulation Of Autophagy Regulation Of Exocytosis Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Post-translational Protein Modification Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Vesicle Fusion To Target Membrane Regulation Of Protein Transport Cilium Assembly Protein Localization To Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse	Protein Phosphorylation Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Cell Cycle Positive Regulation Of Cell Proliferation Negative Regulation Of Endopeptidase Activity Protein Ubiquitination Regulation Of Cytokinesis Regulation Of Cell Proliferation Negative Regulation Of Apoptotic Process Cell Division Labyrinthine Layer Development Spongiotrophoblast Layer Development Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252)	Chronotype ( 30696823) Coffee consumption ( 31046077) General risk tolerance (MTAG) ( 30643258) Male-pattern baldness ( 28196072) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		34 interacting genes: ASNS BAG6 BIRC6 GDI2 IKBKG JAK3 KCNN1 MALT1 MAP4K2 MDM2 MYO5C MYO9B NR2F6 OCRL ODF2 OPTN PDE6D PQBP1 PRKACA RAB11A RAB13 RAB3IL1 RAB3IP RABIF RIMS2 RPH3A RPH3AL STEAP1 SYTL1 SYTL4 TAS2R9 TFRC TPM4 UGT2B15	19 interacting genes: BIRC5 CASP3 CASP7 CASP8 CASP9 CDK1 CSNK2A1 DIABLO EXOC3 EXOC4 GABARAP HTRA2 MAP2K1 PLK1 RAB8A RNF41 UBE2D1 USP8 VAV2
Entrez ID		4218	57448
HPRD ID		01296	05731
Ensembl ID		ENSG00000167461	ENSG00000115760
Uniprot IDs		A0A024R7I3 P61006	Q9NR09
PDB IDs		3QBT 3TNF 4LHV 4LHW 4LHX 4LHY 4LHZ 4LI0 5SZI	3CEG
Enriched GO Terms of Interacting Partners?
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