MDH2 and FH

Number of citations of the paper that reports this interaction (PubMedID 2759092)
2

Data Source:
HPRD (in vitro)

		MDH2	FH
Description		malate dehydrogenase 2	fumarate hydratase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Membrane Extracellular Exosome	Nucleus Chromosome Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Tricarboxylic Acid Cycle Enzyme Complex Extracellular Exosome
	Molecular Function	RNA Binding L-malate Dehydrogenase Activity Protein Self-association Malate Dehydrogenase (NADP+) Activity	Fumarate Hydratase Activity Protein Binding
	Biological Process	Gluconeogenesis Tricarboxylic Acid Cycle Oxaloacetate Metabolic Process Malate Metabolic Process Internal Protein Amino Acid Acetylation NADH Metabolic Process Aerobic Respiration	Tricarboxylic Acid Cycle Fumarate Metabolic Process Malate Metabolic Process DNA Repair Homeostasis Of Number Of Cells Within A Tissue Positive Regulation Of Cold-induced Thermogenesis
Pathways		Gluconeogenesis Citric acid cycle (TCA cycle)	Citric acid cycle (TCA cycle)
Drugs		NADH Citric Acid Xanthinol
Diseases			Renal cell carcinoma Multiple cutaneous and uterine leiomyomata Diseases of the tricarboxylic acid cycle, including: Fumarase (FH) deficiency; Succinate dehydrogenase (SDH) deficiency; Alpha-ketoglutarate dehydrogenase (AKGDH) deficiency
GWAS			Daytime sleep phenotypes ( 27126917) Major depressive disorder ( 27479909) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: CRYAB CS FH GOT2 HSPB1 NDUFS1 PC WARS1	6 interacting genes: CCNDBP1 GRB2 H2AZ1 MDH2 PIM1 PRKDC
Entrez ID		4191	2271
HPRD ID		01099	00652
Ensembl ID		ENSG00000146701	ENSG00000091483
Uniprot IDs		A0A024R4K3 B3KTM1 G3XAL0 P40926	A0A0S2Z4C3 P07954
PDB IDs		2DFD 4WLE 4WLF 4WLN 4WLO 4WLU 4WLV	3E04 5D6B 5UPP 6EBT
Enriched GO Terms of Interacting Partners?
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