| Description |
megakaryocyte-associated tyrosine kinase |
protein tyrosine phosphatase receptor type D |
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| GO Annotations |
Cellular Component |
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| Molecular Function |
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| Biological Process |
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| Pathways |
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| Drugs |
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| Diseases |
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| GWAS |
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- Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
- Airflow obstruction ( 22837378)
- Anxiety and major depressive disorder ( 24047446)
- Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
- Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
- Bitter alcoholic beverage consumption ( 31046077)
- Body mass index (change over time) in gastrointestinal cancer or chronic obstructive pulmonary disease ( 28044437)
- Cardiac Troponin-T levels ( 31014085)
- Cerebrospinal P-tau181p levels ( 28247064)
- Chronotype ( 30696823)
- Diastolic blood pressure ( 30224653)
- Early age at menarche ( 29773799)
- Endometrial cancer (endometrioid histology) ( 30093612)
- Endometriosis or endometrial cancer (pleiotropy) ( 29608257)
- Epilepsy (remission after treatment) ( 23962720)
- Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243)
- Gait rhythm ( 26219847)
- Glycine levels ( 31070104)
- Gout ( 22179738)
- Heel bone mineral density ( 30598549)
- Immune response to measles-mumps-rubella vaccine ( 24811271)
- Intracranial aneurysm ( 29531279)
- Lean body mass ( 28552196)
- Loneliness ( 27629369)
- Loneliness (linear analysis) ( 27629369)
- Loneliness (multivariate analysis) ( 27629369)
- Low susceptibility to hepatitis C infection ( 31206233)
- Menarche (age at onset) ( 29773799 25231870)
- Metabolite levels ( 23823483)
- Midgestational circulating levels of PCBs (fetal genetic effect) ( 28235828)
- Moderate-to-late spontaneous preterm birth ( 31194736)
- Modic changes ( 30808802)
- Mood instability ( 29187730)
- Morning person ( 30696823)
- Myopia (pathological) ( 23049088)
- Non-alcoholic fatty liver disease activity score ( 31311600)
- Non-response to antidepressants and depression ( 27622933)
- Obesity-related traits ( 23251661)
- Obsessive-compulsive disorder ( 24821223)
- Palmitic acid (16:0) levels ( 23362303)
- Partial epilepsies ( 20522523)
- Pelvic organ prolapse (moderate/severe) ( 26545240)
- Personality dimensions ( 23903073)
- Pit-and-Fissure caries ( 24556642)
- Plasma clusterin levels ( 26545630)
- Platelet aggregation ( 20526338)
- Post bronchodilator FEV1 ( 26634245)
- Post bronchodilator FEV1 in COPD ( 26634245)
- Post bronchodilator FEV1/FVC ratio ( 26634245)
- Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
- Pulse pressure ( 27841878)
- Pursuit maintenance gain ( 29064472)
- Resistant hypertension ( 30237584)
- Resting-state electroencephalogram vigilance ( 29703947)
- Restless legs syndrome ( 18660810 29029846 21779176)
- Short-term memory (digit-span task) ( 30741946)
- Subcutaneous adipose tissue ( 26480920)
- Systolic blood pressure ( 30224653 27841878)
- Temperament ( 22832960)
- Third ventricle volume ( 31530798)
- Type 2 diabetes ( 21647700 20174558)
- Waist-hip ratio ( 28552196)
- Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
- White matter hyperintensities in ischemic stroke ( 26674333)
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| Interacting Genes |
20 interacting genes:
AKT1
CACNA1A
CD36
ERBB2
EWSR1
FRS3
HSPA5
HSPA9
ILK
KIT
LRRK1
LRRK2
LYN
NTRK1
PTK2B
PTPRD
PXN
SIRPA
SMURF1
SRC
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33 interacting genes:
ABLIM1
AURKA
BMX
CSNK1D
CSNK1E
DDX17
DDX54
EPHA8
GPC4
IL1RAP
IRS1
MARK2
MATK
MTNR1A
MTNR1B
MTSS1
NEK1
NEK2
NEK6
PAK6
PLK1
PPFIA1
PPFIA2
PPFIA3
PTPRA
PTPRE
PTPRF
PTPRS
SCEL
SLAIN2
SMTNL2
TBK1
TSSK2
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| Entrez ID |
4145 |
5789 |
| HPRD ID |
02496 |
03358 |
| Ensembl ID |
ENSG00000007264
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ENSG00000153707
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| Uniprot IDs |
F1T0G6
P42679
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P23468
Q2HXI4
Q3KPI9
Q59H90
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| PDB IDs |
1JWO
1X6G
3US4
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1X5Z
2DLH
2YD6
2YD7
4RCA
5WY8
5XNP
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| Enriched GO Terms of Interacting Partners? |
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| Tagcloud (Intersection) ? |
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