CASK and TBR1

Number of citations of the paper that reports this interaction (PubMedID 10749215)
77

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		CASK	TBR1
Description		calcium/calmodulin dependent serine protein kinase	T-box brain transcription factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Basement Membrane Nuclear Lamina Nucleolus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Actin Cytoskeleton Basolateral Plasma Membrane Nuclear Matrix Vesicle Presynaptic Membrane Ciliary Membrane Schaffer Collateral - CA1 Synapse	Nucleus
	Molecular Function	Guanylate Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding Calmodulin Binding ATP Binding Neurexin Family Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Kinase Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Protein Phosphorylation Cell Adhesion Neurotransmitter Secretion Negative Regulation Of Keratinocyte Proliferation Positive Regulation Of Transcription By RNA Polymerase II GMP Metabolic Process GDP Metabolic Process Negative Regulation Of Wound Healing Calcium Ion Import Positive Regulation Of Calcium Ion Import Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Synaptic Vesicle Exocytosis	Negative Regulation Of Transcription By RNA Polymerase II Conditioned Taste Aversion Cell Fate Specification Heart Looping Brain Development Specification Of Animal Organ Identity Regulation Of Neuron Projection Development Amygdala Development Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Cerebral Cortex Development Hindbrain Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Axon Guidance
Pathways		Dopamine Neurotransmitter Release Cycle Syndecan interactions Nephrin family interactions Neurexins and neuroligins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs		Formic Acid
Diseases		FG syndrome (FGS); Opitz-Kaveggia syndrome
GWAS			Educational attainment ( 25201988) Intelligence (MTAG) ( 29326435) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Smoking status (ever vs never smokers) ( 30643258) Tourette syndrome ( 30818990)
Interacting Genes		85 interacting genes: AKAP9 APBA1 ATP2B4 BNIP3L CADM1 CASKIN1 CDK9 CNTNAP2 CNTNAP4 DDX54 DLG1 DLG4 DNAJC5 DUSP3 ELL2 EPB41 EPS8 ERBIN F11R FCHSD2 FMR1 GCNT3 GLS2 GRIK2 GRIN2A GTSE1 HGS ID1 IL15RA IL18 KCNA4 KCNJ12 KCNJ2 KCNJ4 KIF2A KLC4 LIN7A LIN7B MAPRE1 MAPRE2 MARK2 MARS1 MED1 MLLT6 NDEL1 NPHS1 NRXN1 NRXN2 NRXN3 P2RX7 PARD3B PARD6G PCBP2 PCM1 PKP2 PLK2 PPP4R3A PRC1 PRKCI PRKD2 PRKN PRPF3 PTGS2 RAB3A RBBP6 RBM10 RBM14 RBM5 RPA2 RPH3A SDC1 SDC2 SDC3 SDC4 SF3B2 SH2D4A SLAIN2 SRPK2 TANC1 TBR1 TRIM22 TSPYL2 WHRN WNT7B YWHAE	1 interacting genes: CASK
Entrez ID		8573	10716
HPRD ID		02164	07055
Ensembl ID		ENSG00000147044	ENSG00000136535
Uniprot IDs		A0A2R8Y6F8 A0A2R8YE77 O14936	Q16650
PDB IDs		1KGD 1KWA 1ZL8 3C0G 3C0H 3C0I 3MFR 3MFS 3MFT 3MFU 3TAC
Enriched GO Terms of Interacting Partners?
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