MARK1 and ESRRG

		MARK1	ESRRG
Description		microtubule affinity regulating kinase 1	estrogen related receptor gamma
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Dendrite	Nuclear Chromatin Nucleoplasm
	Molecular Function	Magnesium Ion Binding Phosphatidylserine Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Tau Protein Binding Tau-protein Kinase Activity Phosphatidic Acid Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Steroid Binding Protein Binding Zinc Ion Binding AF-2 Domain Binding
	Biological Process	Microtubule Cytoskeleton Organization Neuron Migration Protein Phosphorylation Cytoskeleton Organization Regulation Of Neuron Projection Development Wnt Signaling Pathway Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Dendrite Development Establishment Of Mitochondrion Localization	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis
Pathways			Nuclear Receptor transcription pathway
Drugs			Troglitazone Diethylstilbestrol Tamoxifen Estradiol Cholic Acid Afimoxifene 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE 4-(1-methyl-1-phenylethyl)phenol 4,4'-PROPANE-2,2-DIYLDIPHENOL 4,4'-cyclohexane-1,1-diyldiphenol
Diseases
GWAS		Bipolar disorder ( 22205951) Breast size ( 27182965) Fat distribution (HIV) ( 21897333)	Adventurousness ( 30643258) Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065) Adverse response to drug ( 30420678) Alcohol consumption ( 23743675) Breast cancer ( 29059683) Cardiac hypertrophy ( 21348951) Cleft lip with or without cleft palate (maternal periconceptional vitamin use interaction) ( 29535761) Depressive symptom (anhedonia) (ordinal trait) ( 31530331) Dialysis-related mortality ( 21546767) Energy expenditure (24h) ( 28476931) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Intelligence (MTAG) ( 29326435) Intracranial aneurysm ( 29531279) Major depressive disorder ( 23377640) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Optic nerve measurement (cup area) ( 20395239) Photic sneeze reflex ( 27182965) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Sleep duration ( 25469926) Smoking status (ever vs never smokers) ( 30643258) Tea consumption ( 31046077) Weight ( 28552196)
Interacting Genes		13 interacting genes: CCDC102B CCR6 ESRRG GJA5 KCNK2 MAP2 MAP4 MAPT NIBAN1 STK11 TAOK1 TGFB2 USH2A	32 interacting genes: APP ARHGEF15 CALM1 DAXX DEUP1 DUT EBP ESRRA HGS HIF1A KIFC3 LRRK2 MARK1 MEOX2 MFHAS1 NCOA1 NR0B1 NR0B2 NRIP1 NUP160 PNRC1 PNRC2 PPARGC1A PPARGC1B PROX1 PSMC5 SHTN1 SP1 SRA1 SRPK1 SUMO1P1 TLE1
Entrez ID		4139	2104
HPRD ID		07353	04274
Ensembl ID		ENSG00000116141	ENSG00000196482
Uniprot IDs		A0A087X0I6 B4DIB3 Q9P0L2 X5D2M4	B7Z5E9 C0SQ93 F1D8R5 F1D8R6 P62508
PDB IDs		2HAK 3OSE 6C9D	1KV6 1TFC 1VJB 2E2R 2EWP 2GP7 2GPO 2GPP 2GPU 2GPV 2P7A 2P7G 2P7Z 2ZAS 2ZBS 2ZKC 5YSO 6A6K 6I61 6I62 6I63 6I64 6I65 6I66 6I67
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?