ESRRG and DUT

Number of citations of the paper that reports this interaction (PubMedID 15604093)
54

Data Source:
HPRD (two hybrid)

		ESRRG	DUT
Description		estrogen related receptor gamma	deoxyuridine triphosphatase
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm	Nucleus Nucleoplasm Mitochondrion Extracellular Exosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Steroid Binding Protein Binding Zinc Ion Binding AF-2 Domain Binding	Magnesium Ion Binding RNA Binding DUTP Diphosphatase Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis	Nucleobase-containing Compound Metabolic Process DUMP Biosynthetic Process DNA Replication Nucleobase-containing Small Molecule Interconversion DUTP Catabolic Process
Pathways		Nuclear Receptor transcription pathway
Drugs		Troglitazone Diethylstilbestrol Tamoxifen Estradiol Cholic Acid Afimoxifene 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE 4-(1-methyl-1-phenylethyl)phenol 4,4'-PROPANE-2,2-DIYLDIPHENOL 4,4'-cyclohexane-1,1-diyldiphenol	Deoxyuridine-5'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS		Adventurousness ( 30643258) Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065) Adverse response to drug ( 30420678) Alcohol consumption ( 23743675) Breast cancer ( 29059683) Cardiac hypertrophy ( 21348951) Cleft lip with or without cleft palate (maternal periconceptional vitamin use interaction) ( 29535761) Depressive symptom (anhedonia) (ordinal trait) ( 31530331) Dialysis-related mortality ( 21546767) Energy expenditure (24h) ( 28476931) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Intelligence (MTAG) ( 29326435) Intracranial aneurysm ( 29531279) Major depressive disorder ( 23377640) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Optic nerve measurement (cup area) ( 20395239) Photic sneeze reflex ( 27182965) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Sleep duration ( 25469926) Smoking status (ever vs never smokers) ( 30643258) Tea consumption ( 31046077) Weight ( 28552196)	Blood protein levels ( 30072576) Height ( 31562340) Protein quantitative trait loci ( 18464913) Skin pigmentation ( 28300201)
Interacting Genes		32 interacting genes: APP ARHGEF15 CALM1 DAXX DEUP1 DUT EBP ESRRA HGS HIF1A KIFC3 LRRK2 MARK1 MEOX2 MFHAS1 NCOA1 NR0B1 NR0B2 NRIP1 NUP160 PNRC1 PNRC2 PPARGC1A PPARGC1B PROX1 PSMC5 SHTN1 SP1 SRA1 SRPK1 SUMO1P1 TLE1	9 interacting genes: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2
Entrez ID		2104	1854
HPRD ID		04274	03165
Ensembl ID		ENSG00000196482	ENSG00000128951
Uniprot IDs		B7Z5E9 C0SQ93 F1D8R5 F1D8R6 P62508	A0A0C4DGL3 H0YNW5 P33316
PDB IDs		1KV6 1TFC 1VJB 2E2R 2EWP 2GP7 2GPO 2GPP 2GPU 2GPV 2P7A 2P7G 2P7Z 2ZAS 2ZBS 2ZKC 5YSO 6A6K 6I61 6I62 6I63 6I64 6I65 6I66 6I67	1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4MZ5 4MZ6 5H4J
Enriched GO Terms of Interacting Partners?
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