FAM74A1 and ID3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FAM74A1	ID3
Description		family with sequence similarity 74 member A1	inhibitor of DNA binding 3, HLH protein
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleus
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Dimerization Activity Transcription Regulator Activity Leptomycin B Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Regulation Of DNA Replication Multicellular Organism Development Central Nervous System Development Heart Development Muscle Organ Development Response To Wounding Positive Regulation Of Gene Expression Cell Differentiation Epithelial Cell Differentiation Notochord Development Circadian Regulation Of Gene Expression Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Leptomycin B Positive Regulation Of Nucleic Acid-templated Transcription
Pathways			NGF-stimulated transcription
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: ID3 PHC2	37 interacting genes: ADD1 ATF3 CBFA2T2 CDK2 CEP350 CNOT3 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 GATA4 GNB2 GTF2A1L HES1 ID4 IFI16 IKBKG MLX MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626
Entrez ID		401507	3399
HPRD ID		17394	02608
Ensembl ID		ENSG00000215112	ENSG00000117318
Uniprot IDs			Q02535
PDB IDs			2LFH
Enriched GO Terms of Interacting Partners?
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