RHOH and ARHGDIG

Number of citations of the paper that reports this interaction (PubMedID 11809807)
34

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		RHOH	ARHGDIG
Description		ras homolog family member H	Rho GDP dissociation inhibitor gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Cytoplasm Cytosol Plasma Membrane	Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Rho GTPase Binding Kinase Inhibitor Activity	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Rac GTPase Binding
	Biological Process	Regulation Of Transcription, DNA-templated Rho Protein Signal Transduction T Cell Differentiation Negative Regulation Of Kinase Activity Negative Regulation Of GTPase Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction	Blastocyst Hatching Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Protein Localization Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle	Rho GTPase cycle
Drugs
Diseases
GWAS		Graves' disease ( 21841780) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)	Body mass index ( 26426971)
Interacting Genes		8 interacting genes: ARHGDIA ARHGDIB ARHGDIG GDI1 KCNH2 LRIF1 TGFBR1 UTP14A	8 interacting genes: CDC42 CEP170P1 KXD1 RAC1 RHOA RHOB RHOG RHOH
Entrez ID		399	398
HPRD ID		03616	04163
Ensembl ID		ENSG00000168421	ENSG00000242173
Uniprot IDs		Q15669 Q6ICP4	F1T0H7 Q99819
PDB IDs
Enriched GO Terms of Interacting Partners?
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