ARHGDIG and RHOH

Number of citations of the paper that reports this interaction (PubMedID 11809807)
34

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		ARHGDIG	RHOH
Description		Rho GDP dissociation inhibitor gamma	ras homolog family member H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle	Immunological Synapse Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Rac GTPase Binding	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Rho GTPase Binding Kinase Inhibitor Activity
	Biological Process	Blastocyst Hatching Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Protein Localization Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Regulation Of Transcription, DNA-templated Rho Protein Signal Transduction T Cell Differentiation Negative Regulation Of Kinase Activity Negative Regulation Of GTPase Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle	Rho GTPase cycle
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Graves' disease ( 21841780) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		8 interacting genes: CDC42 CEP170P1 KXD1 RAC1 RHOA RHOB RHOG RHOH	8 interacting genes: ARHGDIA ARHGDIB ARHGDIG GDI1 KCNH2 LRIF1 TGFBR1 UTP14A
Entrez ID		398	399
HPRD ID		04163	03616
Ensembl ID		ENSG00000242173	ENSG00000168421
Uniprot IDs		F1T0H7 Q99819	Q15669 Q6ICP4
PDB IDs
Enriched GO Terms of Interacting Partners?
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