ARHGDIB and RHOH

Number of citations of the paper that reports this interaction (PubMedID 11809807)
34

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro, two hybrid)

		ARHGDIB	RHOH
Description		Rho GDP dissociation inhibitor beta	ras homolog family member H
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Membrane Cytoplasmic Vesicle Extracellular Exosome	Immunological Synapse Cytoplasm Cytosol Plasma Membrane
	Molecular Function	GTPase Activity Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Rac GTPase Binding	GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Rho GTPase Binding Kinase Inhibitor Activity
	Biological Process	Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Multicellular Organism Development Regulation Of Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Cellular Response To Redox State Negative Regulation Of Trophoblast Cell Migration Regulation Of Actin Cytoskeleton Reorganization	Regulation Of Transcription, DNA-templated Rho Protein Signal Transduction T Cell Differentiation Negative Regulation Of Kinase Activity Negative Regulation Of GTPase Activity Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mast Cell Activation Positive Regulation Of T Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle	Rho GTPase cycle
Drugs
Diseases
GWAS			Graves' disease ( 21841780) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		12 interacting genes: APP CASP3 CDC42 EZR RAC1 RAC2 RAC3 RHOA RHOH UBE3A UFM1 VAV1	8 interacting genes: ARHGDIA ARHGDIB ARHGDIG GDI1 KCNH2 LRIF1 TGFBR1 UTP14A
Entrez ID		397	399
HPRD ID		04162	03616
Ensembl ID		ENSG00000111348	ENSG00000168421
Uniprot IDs		A0A024RAS5 P52566	Q15669 Q6ICP4
PDB IDs		1DS6 5H1D
Enriched GO Terms of Interacting Partners?
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