LGALS8 and TRIM5

Number of citations of the paper that reports this interaction (PubMedID 27693506)
64

Data Source:
BioGRID (pull down)

		LGALS8	TRIM5
Description		galectin 8	tripartite motif containing 5
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle	P-body Nucleus Cytoplasm Cytosol Omegasome
	Molecular Function	Integrin Binding Protein Binding Carbohydrate Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Binding, Bridging Pattern Recognition Receptor Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Cellular Response To Virus Xenophagy Lymphatic Endothelial Cell Migration	Activation Of Innate Immune Response Autophagy Viral Process Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Protein K63-linked Ubiquitination Negative Regulation Of Viral Release From Host Cell
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) DNA methylation (variation) ( 23725790) Mean platelet volume ( 27863252) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Platelet count ( 29403010) Serum alkaline phosphatase levels ( 29403010)
Interacting Genes		16 interacting genes: APEH BARD1 CALCOCO2 ITGA3 ITGA4 ITGB1 LRRK2 MEFV MID2 TAX1BP1 TRIM17 TRIM22 TRIM23 TRIM49 TRIM5 TRIM6	38 interacting genes: BTBD1 BTBD2 EWSR1 LGALS8 LZTR1 MKRN3 MNAT1 OTUB2 OTUD6A PCBD1 PIAS1 PRKCG PSMC2 RUNX1 TNFAIP3 TRIM21 TRIM32 TRIM34 TRIM35 TRIM6 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2H UBE2K UBE2N UBE2U UBE2V1 UBE2V2 UBE2W USP15 USP2 USP21 USP39 USP5
Entrez ID		3964	85363
HPRD ID		09356	07004
Ensembl ID		ENSG00000116977	ENSG00000132256
Uniprot IDs		O00214	Q9C035
PDB IDs		2YRO 2YV8 2YXS 3AP4 3AP5 3AP6 3AP7 3AP9 3APB 3OJB 3VKL 3VKM 3VKN 3VKO 4BMB 4BME 4FQZ 4GXL 4HAN 5GZC 5GZD 5GZE 5GZF 5GZG 5T7I 5T7S 5T7T 5T7U 5VWG	2ECV 2YRG
Enriched GO Terms of Interacting Partners?
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