GOLGA8EP and CBX5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GOLGA8EP	CBX5
Description		golgin A8 family member E, pseudogene	chromobox 5
Image		No pdb structure
GO Annotations	Cellular Component		Histone Deacetylase Complex Kinetochore Nuclear Chromosome, Telomeric Region Nucleus Nuclear Envelope Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Nucleolus Chromocenter PML Body Transcriptional Repressor Complex Nuclear Pericentric Heterochromatin Protein-containing Complex Histone Methyltransferase Complex Site Of DNA Damage Ribonucleoprotein Complex
	Molecular Function		Chromatin Binding Protein Binding Protein Binding, Bridging Methylated Histone Binding Identical Protein Binding Histone Deacetylase Binding Ribonucleoprotein Complex Binding Protein-containing Complex Binding Repressing Transcription Factor Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Blood Coagulation Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6 Factors involved in megakaryocyte development and platelet production
Drugs			Copper
Diseases
GWAS			Alcohol consumption ( 31358974) Blood protein levels ( 30072576) Hip circumference ( 28552196) Mean platelet volume ( 22139419) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		24 interacting genes: ADAMTSL4 ATF4 BAAT BEX3 CBX5 CDC5L EPS8 GOSR2 HDDC3 KCTD6 KRT13 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 MEOX2 NMI PDE4D PDE4DIP SPAG5 STX11 TCF4 USHBP1 ZNF471	55 interacting genes: ARHGDIA ARL5A BAP1 BARD1 BCL11B BRCA1 CBX1 CBX3 CHAF1A DNMT3B DSN1 ELOA2 ELOC FSHR GOLGA8EP H1-4 H1-5 H2AW H2BU1 H3-4 H3C15 H4-16 HDAC4 HDAC5 HDAC9 HECW2 INCENP LBR LRIF1 MBD1 MCC MIS12 MKI67 NIPBL NR2F1 NSD3 NSL1 PRR14 RPSA SMARCA4 SP1 SP100 SRPK1 SRPK2 STAM2 SUB1 SUV39H1 TAF4 TRIM24 TRIM28 UBE2A UBE2B VPS28 XRCC6 XRN1
Entrez ID		390535	23468
HPRD ID		17381	05131
Ensembl ID			ENSG00000094916
Uniprot IDs			P45973 V9HWG0
PDB IDs			3FDT 3I3C
Enriched GO Terms of Interacting Partners?
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