MAFA and NEUROD1

Number of citations of the paper that reports this interaction (PubMedID 15665000)
70

Data Source:
HPRD (in vivo, in vitro)

		MAFA	NEUROD1
Description		MAF bZIP transcription factor A	neuronal differentiation 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nuclear Chromatin Cell Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	Regulation Of Transcription, DNA-templated Nitric Oxide Mediated Signal Transduction Response To Glucose Insulin Secretion Positive Regulation Of Transcription By RNA Polymerase II	Pancreatic A Cell Fate Commitment Pancreatic PP Cell Fate Commitment Nucleocytoplasmic Transport Nitric Oxide Mediated Signal Transduction Response To Glucose Anterior/posterior Pattern Specification Dentate Gyrus Development Cerebellum Development Neurogenesis Signal Transduction Involved In Regulation Of Gene Expression Insulin Secretion Endocrine Pancreas Development Amacrine Cell Differentiation Enteroendocrine Cell Differentiation Response To Drug Glucose Homeostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of JAK-STAT Cascade Embryonic Organ Morphogenesis Neuron Development Inner Ear Development Regulation Of Insulin Secretion Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Intestinal Epithelial Structure Maintenance Regulation Of Cell Cycle Arrest Cellular Response To Glucose Stimulus Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Positive Regulation Of Transcription Regulatory Region DNA Binding
Pathways		Regulation of gene expression in beta cells	Regulation of gene expression in beta cells Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
Drugs
Diseases			Maturity onset diabetes of the young (MODY)
GWAS		Nonsyndromic cleft palate ( 31609978)	Glucosuria ( 30476138) Glucosuria (moderate to severe) ( 30476138)
Interacting Genes		5 interacting genes: MAF MAPK1 MAPK14 NEUROD1 PDX1	14 interacting genes: CALM1 CALM2 CALM3 DUSP3 EP300 HAP1 MAFA MAP3K10 NR0B2 PDX1 PITX1 RREB1 TCF3 TCF4
Entrez ID		389692	4760
HPRD ID		14346	03428
Ensembl ID		ENSG00000182759	ENSG00000162992
Uniprot IDs		Q8NHW3	Q13562
PDB IDs		4EOT
Enriched GO Terms of Interacting Partners?
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