MAFA and MAF

Number of citations of the paper that reports this interaction (PubMedID 12011435)
96

Data Source:
HPRD (in vitro)

		MAFA	MAF
Description		MAF bZIP transcription factor A	MAF bZIP transcription factor
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Chromatin Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Nitric Oxide Mediated Signal Transduction Response To Glucose Insulin Secretion Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Cytokine Production Transcription By RNA Polymerase II Regulation Of Chondrocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development Inner Ear Development Lens Fiber Cell Differentiation
Pathways		Regulation of gene expression in beta cells	RUNX2 regulates osteoblast differentiation
Drugs
Diseases			Multiple myeloma
GWAS		Nonsyndromic cleft palate ( 31609978)	Alzheimer's disease (late onset) ( 30820047) Colorectal cancer ( 30529582) Depressive symptoms (SSRI exposure interaction) ( 25649181) Estimated glomerular filtration rate ( 31015462) Height ( 20668459) Lysophosphatidylcholine levels ( 31551469) Macular thickness ( 30535121) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244 24076602 21833088) Obesity ( 19151714) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Renal function-related traits (urea) ( 22797727) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Serum alkaline phosphatase levels ( 29403010) Serum thyroid-stimulating hormone levels ( 24852370) Serum uric acid levels ( 30993211) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335) Thyroid volume ( 21565293) Urate levels ( 23263486)
Interacting Genes		5 interacting genes: MAF MAPK1 MAPK14 NEUROD1 PDX1	17 interacting genes: ATF4 CREBBP EP300 ETS1 FOS FOSL1 HOXD12 JUN MAFA MAFB MAFG MYB NEU1 SMARCA5 SOX9 UBE2O USF2
Entrez ID		389692	4094
HPRD ID		14346	01518
Ensembl ID		ENSG00000182759	ENSG00000178573
Uniprot IDs		Q8NHW3	H3BP11 O75444
PDB IDs		4EOT
Enriched GO Terms of Interacting Partners?
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