INKA1 and PAK5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		INKA1	PAK5
Description		inka box actin regulator 1	p21 (RAC1) activated kinase 5
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm Mitochondrion Synapse
	Molecular Function	Protein Binding Protein Kinase Binding Protein Serine/threonine Kinase Inhibitor Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Neural Tube Development Negative Regulation Of Protein Serine/threonine Kinase Activity	Regulation Of Cell Growth Apoptotic Process Cytoskeleton Organization Signal Transduction Regulation Of Mitotic Cell Cycle Learning Memory Locomotory Behavior Cell Proliferation Cell Migration Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Activation of RAC1
Drugs
Diseases
GWAS			Atopy ( 28927820) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)
Interacting Genes		2 interacting genes: APP PAK5	21 interacting genes: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FHL3 GCC1 INKA1 LENG1 LZTS2 PDLIM7 PRPF31 PSMF1 RAC1 SORBS3 TUBGCP4 UXT
Entrez ID		389119	57144
HPRD ID		14210	06423
Ensembl ID		ENSG00000185614	ENSG00000101349
Uniprot IDs		Q96EL1	B0AZM9 Q9P286
PDB IDs		4XBR 4XBU	2F57
Enriched GO Terms of Interacting Partners?
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