KRTAP10-1 and WT1

Number of citations of the paper that reports this interaction (PubMedID 27229929)
3

Data Source:
BioGRID (two hybrid)

		KRTAP10-1	WT1
Description		keratin associated protein 10-1	WT1 transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Nuclear Speck
	Molecular Function		DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Double-stranded Methylated DNA Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Hemi-methylated DNA-binding C2H2 Zinc Finger Domain Binding
	Biological Process	Keratinization	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Ureteric Bud Development Branching Involved In Ureteric Bud Morphogenesis Kidney Development Regulation Of Animal Organ Formation Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Germ Cell Development Thorax And Anterior Abdomen Determination Heart Development Sex Determination Negative Regulation Of Cell Proliferation RNA Splicing Gonad Development Male Gonad Development Tissue Development Positive Regulation Of Gene Expression Negative Regulation Of Cell Growth Adrenal Gland Development Male Genitalia Development Epithelial Cell Differentiation Glomerulus Development Glomerular Basement Membrane Development Adrenal Cortex Formation Camera-type Eye Development Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Mesenchymal To Epithelial Transition Positive Regulation Of Heart Growth Diaphragm Development Cardiac Muscle Cell Fate Commitment Visceral Serous Pericardium Development Cellular Response To CAMP Cellular Response To Gonadotropin Stimulus Metanephric Mesenchyme Development Glomerular Visceral Epithelial Cell Differentiation Posterior Mesonephric Tubule Development Metanephric Epithelium Development Metanephric S-shaped Body Morphogenesis Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of DNA Methylation Positive Regulation Of Male Gonad Development Negative Regulation Of Female Gonad Development Positive Regulation Of Metanephric Ureteric Bud Development
Pathways		Keratinization
Drugs
Diseases			Nephrotic syndrome and focal segmental glomerulosclerosis 46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS			Birth weight ( 31043758) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Inguinal hernia ( 26686553) Medication use (diuretics) ( 31015401) Offspring birth weight ( 31043758) Pulse pressure ( 30224653) Resting-state electroencephalogram vigilance ( 29703947) Rubella-specific interleukin-6 secretion ( 29253144) Tuberculosis ( 24057671 22306650) Uterine fibroids ( 31249589 30194396 31649266)
Interacting Genes		75 interacting genes: ADAMTSL4 AEN AMMECR1 AVPI1 BAHD1 BCL6B CARD9 CATSPER1 CBX2 CHIC2 CHRD CREB5 CXCL16 DAAM2 DHX57 DKK1 DOCK2 ECE1 FAM76B GLRX3 HOXA1 HPCAL1 HSD3B7 KRTAP10-3 KRTAP12-1 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E MAPKBP1 MEOX2 MOBP NECTIN2 NOTCH2NLA NPDC1 NR4A1 OTX1 PID1 PIN1 POM121L8P PRM2 PRPF31 RSPO2 SHFL SLC23A1 SLC6A20 SPATA8 SPRY1 SPRY2 TULP3 WT1 ZBTB24 ZNF101 ZNF124 ZNF264 ZNF286A ZNF329 ZNF417 ZNF433 ZNF439 ZNF440 ZNF559 ZNF572 ZNF581 ZNF587 ZNF785 ZSCAN12 ZSCAN26	55 interacting genes: AREG CASZ1 CCDC136 CCDC33 CCL5 CEP70 CIAO1 CREBBP DIRAS3 DVL2 DVL3 EGR1 ETV7 FAM9B FHL2 FMR1NB GLIS2 GOLGA2 HMBOX1 IDI1 KLK7 KPNA4 KPNA5 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 LDOC1 MAGEA8 MDM2 MYC NAT2 NPM3 PAWR PAX2 PRKACA RNASEH2B SERF2 SOX4 STK11 TAOK1 THAP1 THRSP TP53 TP63 TP73 U2AF2 UBE2I WTAP WTIP ZNF205
Entrez ID		386677	7490
HPRD ID		11184	06163
Ensembl ID		ENSG00000215455	ENSG00000184937
Uniprot IDs		P60331	P19544 Q6PI38
PDB IDs			1LU6 1XF7 2G7T 2G7V 2G7W 2G7X 2JP9 2JPA 2PRT 3HPJ 3MYJ 4R2E 4R2P 4R2Q 4R2R 4R2S 4WUU 5KL2 5KL3 5KL4 5KL5 5KL6 5KL7 6B0O 6B0P 6B0Q 6B0R 6BLW
Enriched GO Terms of Interacting Partners?
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