KRT2 and KRT19

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		KRT2	KRT19
Description		keratin 2	keratin 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleus Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Cytosol Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Extracellular Exosome Cell Periphery Terminal Web
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Structural Constituent Of Epidermis	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein-containing Complex Binding
	Biological Process	Keratinocyte Development Epidermis Development Peptide Cross-linking Keratinization Keratinocyte Activation Keratinocyte Proliferation Intermediate Filament Organization Positive Regulation Of Epidermis Development Keratinocyte Migration Cornification	Notch Signaling Pathway Viral Process Keratinization Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Copper
Diseases		Ichthyosis bullosa of Siemens
GWAS
Interacting Genes		9 interacting genes: EVPL KRT13 KRT15 KRT19 KRT31 KRT38 KRT40 SIRPA SMAD3	41 interacting genes: ABI2 AMOTL2 APC C1orf109 CARD9 CCDC146 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP HAUS1 HGS IKZF3 KDM1A KIFC3 KRT15 KRT2 KRT6B PCM1 PLEKHA5 PNN POLR1C PPP1R18 SFI1 SMARCB1 TBC1D7 TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638
Entrez ID		3849	3880
HPRD ID		02560	01007
Ensembl ID		ENSG00000172867	ENSG00000171345
Uniprot IDs		P35908	P08727
PDB IDs
Enriched GO Terms of Interacting Partners?
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