KRT19 and COPS4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		KRT19	COPS4
Description		keratin 19	COP9 signalosome subunit 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Extracellular Exosome Cell Periphery Terminal Web	Nucleus Nucleoplasm Cytosol Synaptic Vesicle COP9 Signalosome Nuclear Speck Cell Junction
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein-containing Complex Binding	Protein Binding NEDD8-specific Protease Activity
	Biological Process	Notch Signaling Pathway Viral Process Keratinization Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development Cornification	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair Post-translational Protein Modification
Pathways		Keratinization Formation of the cornified envelope	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		41 interacting genes: ABI2 AMOTL2 APC C1orf109 CARD9 CCDC146 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP HAUS1 HGS IKZF3 KDM1A KIFC3 KRT15 KRT2 KRT6B PCM1 PLEKHA5 PNN POLR1C PPP1R18 SFI1 SMARCB1 TBC1D7 TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638	19 interacting genes: C19orf57 CCDC85B COPS2 COPS3 COPS5 COPS6 COPS7A COPS8 CUL5 FOS IKBKB IL1RN KRT19 MBIP RCBTB2 TP53 UBQLN1 USHBP1 YWHAQ
Entrez ID		3880	51138
HPRD ID		01007	09888
Ensembl ID		ENSG00000171345	ENSG00000138663
Uniprot IDs		P08727	A0A0S2Z5H7 B3KM48 D6RAX7 Q9BT78
PDB IDs			4D0P 4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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