IVL and KRT1

Number of citations of the paper that reports this interaction (PubMedID 8999895)
28

Data Source:
BioGRID (pull down)

		IVL	KRT1
Description		involucrin	keratin 1
Image
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Centrosome Cytosol Nuclear Body Extracellular Exosome	Cornified Envelope Extracellular Region Extracellular Space Nucleus Cytosol Cytoskeleton Membrane Keratin Filament Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	Protein Binding Carbohydrate Binding Structural Constituent Of Epidermis Signaling Receptor Activity Protein Heterodimerization Activity
	Biological Process	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Cornification	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Peptide Cross-linking Keratinization Fibrinolysis Neutrophil Degranulation Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Protein Heterotetramerization Establishment Of Skin Barrier Cornification
Pathways		Formation of the cornified envelope	Neutrophil degranulation Keratinization Formation of the cornified envelope
Drugs			Zinc Copper
Diseases			Epidermolytic palmoplantar keratoderma (EPPK) Ichthyosis hystrix, Curth-Macklin type Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE) Striate palmoplantar keratoderma
GWAS		Asthma ( 31619474) Vitamin D levels ( 26704534)
Interacting Genes		9 interacting genes: ACD CSTA DSP EVPL KRT1 LORICRIN POT1 SPRR3 UCHL5	21 interacting genes: CALB2 CSTA DSP EVPL F12 FANCA FANCC IVL KNG1 KRT15 KRT33B KRT5 LINC00839 LORICRIN MBL2 NINL PDE4DIP PI3 PRKCE UBE3A YWHAQ
Entrez ID		3713	3848
HPRD ID		00931	00763
Ensembl ID		ENSG00000163207	ENSG00000167768
Uniprot IDs		P07476	P04264
PDB IDs		1EU0	4ZRY 6E2J 6UUI
Enriched GO Terms of Interacting Partners?
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