KLRC1 and PMP22

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KLRC1	PMP22
Description		killer cell lectin like receptor C1	peripheral myelin protein 22
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Compact Myelin Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding Protein Antigen Binding	Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of Immune Response	Chemical Synaptic Transmission Peripheral Nervous System Development Cell Death Negative Regulation Of Cell Proliferation Negative Regulation Of Neuron Projection Development Bleb Assembly Myelin Assembly Myelination
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Blood protein levels ( 28240269) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252)	Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 29566793) Corneal structure ( 23291589) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)
Interacting Genes		6 interacting genes: HLA-E KLRD1 MAL PMP22 PTPN11 PTPN6	8 interacting genes: CANX CREB3 DDX52 KLRC1 LMNA MPZ PEX19 SMIM3
Entrez ID		3821	5376
HPRD ID		01192	03059
Ensembl ID		ENSG00000134545	ENSG00000109099
Uniprot IDs		P26715	A8MU75 Q01453 Q6FH25
PDB IDs		2RMX 2YU7 3BDW 3CDG 3CII
Enriched GO Terms of Interacting Partners?
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