ARF6 and MGAM

		ARF6	MGAM
Description		ADP ribosylation factor 6	maltase-glucoamylase
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GO Annotations	Cellular Component	Ruffle Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Cell Cortex Membrane Endocytic Vesicle Filopodium Membrane Early Endosome Membrane Cleavage Furrow Recycling Endosome Membrane Extracellular Exosome Flemming Body Presynapse Glutamatergic Synapse	Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Thioesterase Binding Protein N-terminus Binding	Catalytic Activity Glucan 1,4-alpha-glucosidase Activity Amylase Activity Carbohydrate Binding Maltose Alpha-glucosidase Activity
	Biological Process	Liver Development Intracellular Protein Transport Cell Cycle Cell Adhesion Vesicle-mediated Transport Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Endocytic Recycling Myeloid Cell Apoptotic Process Protein Localization To Cell Surface Regulation Of Rac Protein Signal Transduction Protein Localization To Endosome Negative Regulation Of Receptor-mediated Endocytosis Synaptic Vesicle Endocytosis Positive Regulation Of Protein Secretion Cell Division Regulation Of Filopodium Assembly Positive Regulation Of Keratinocyte Migration Regulation Of Dendritic Spine Development Establishment Of Epithelial Cell Polarity Ruffle Assembly Hepatocyte Apoptotic Process Maintenance Of Postsynaptic Density Structure Positive Regulation Of Focal Adhesion Disassembly Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Presynapse Assembly Cellular Response To Nerve Growth Factor Stimulus Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Dendrite Development	Maltose Metabolic Process Starch Catabolic Process Neutrophil Degranulation Polysaccharide Digestion
Pathways		TBC/RABGAPs Clathrin-mediated endocytosis MET receptor recycling	Digestion of dietary carbohydrate Neutrophil degranulation
Drugs		5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Diphosphate Myristic acid	Acarbose Miglitol Voglibose
Diseases
GWAS		Erythema nodosum in inflammatory bowel disease ( 24487271)	1,5-anhydroglucitol levels ( 28588231) Anorexia nervosa ( 23568457) Blood metabolite levels ( 24816252) Idiopathic dilated cardiomyopathy ( 29495422)
Interacting Genes		42 interacting genes: AGAP1 ALDH5A1 AP1B1 AP3B1 AP3D1 AP3S2 APP ARFIP2 ARHGAP10 ARRB1 ARRB2 ASAP1 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CYTH1 CYTH2 EXOC5 EZR HTR2A IKBKG ITSN1 LSM7 MGAM MPP5 MT2A PIP5K1A PIP5K1C PLD1 PRPF39 RAB11A RAB11FIP3 RAB11FIP4 RAB11FIP5 RPLP1 SMAP1 SMARCC2 SPAG9 TOGARAM1 ZNF709	2 interacting genes: ARF6 NCF1
Entrez ID		382	8972
HPRD ID		02714	01104
Ensembl ID		ENSG00000165527	ENSG00000257335
Uniprot IDs		P62330	E7ER45 O43451
PDB IDs		1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX 6BBP 6BBQ	2QLY 2QMJ 3CTT 3L4T 3L4U 3L4V 3L4W 3L4X 3L4Y 3L4Z 3TON 3TOP
Enriched GO Terms of Interacting Partners?
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