TSG101 and USHBP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TSG101	USHBP1
Description		tumor susceptibility 101	USH1 protein network component harmonin binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Nucleolus Cytoplasm Endosome Early Endosome Late Endosome Multivesicular Body Microtubule Organizing Center Cytosol Plasma Membrane Endosome Membrane Early Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome Flemming Body
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Nuclear Receptor Transcription Coactivator Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Binding Protein-containing Complex Binding Virion Binding Calcium-dependent Protein Binding	Protein Binding PDZ Domain Binding
	Biological Process	Regulation Of Cell Growth Protein Monoubiquitination Extracellular Transport Cell Cycle Arrest Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Cell Proliferation Endosome To Lysosome Transport Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Keratinocyte Differentiation Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Negative Regulation Of Transcription, DNA-templated Viral Budding Cell Division Intracellular Transport Of Virus Autophagosome Maturation Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Exosome Assembly Positive Regulation Of Viral Budding Via Host ESCRT Complex Exosomal Secretion Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS			Mitochondrial DNA copy number ( 30704525)
Interacting Genes		88 interacting genes: AATF ADRB2 AKAP9 AR ARRDC1 BCAS3 BCR BIRC2 CCND3 CDKN1A CDKN2D CDS2 CEP55 CNOT7 DAXX DMAP1 DMRTB1 DNMT1 DZIP3 EP300 FAM9B GGA1 GGA3 GMCL1 HAUS1 HCK HGS IQGAP1 ITSN1 JUN KIF5A KIFC3 KLK5 KLK6 KRT13 KRT15 KRT31 LRSAM1 MDM2 MGRN1 MKRN3 MTA3 NR3C1 PDCD6IP PDLIM7 PIAS1 PPFIBP2 PRSS50 QKI RAD18 RASL10B RBPMS RNF111 RNF126 RNF41 ROCK1 SCAMP3 SCGB3A1 SCNN1A SH3GLB2 SNF8 SNX32 STK11 SYCE1 TAX1BP1 TEX11 TFF1 THRB THRSP TNIP2 TNNT3 TOM1L1 TP53 TRAIP TRIM23 TRIM35 TRIM46 TRIM74 UBA52 UBC USHBP1 VPS11 VPS28 VPS36 VPS37A VPS37B VPS37C VPS37D	129 interacting genes: ABLIM1 AKAP9 ANKRD36BP1 ARFIP2 ARNT2 ATP5PO BCL10 BET1 BEX3 BFSP2 C1orf109 C1orf216 CCDC116 CCDC120 CCDC121 CCDC146 CCDC148 CCDC22 CCDC24 CCDC33 CCDC87 CCHCR1 CCNK CENPP CEP63 CEP68 CFAP206 CHCHD3 CNNM3 COPS4 COPS8 CTNNBIP1 CTTNBP2NL DEPP1 DTNB DYDC1 EIF4E2 ERCC1 EXOC7 EXOC8 FAM107A FAM110A FAM124B FANCG FATE1 FBF1 FTL GATAD2B GCC1 GFI1B GIT2 GMCL2 GNG4 GOLGA8EP GOLGA8F GPSM1 GPSM3 GTF2H1 HAUS1 HGS IFT20 IL16 IMP3 ING3 INPP1 INTS4 KANSL1 KIAA0753 KLC3 KLC4 KLHL38 KLHL42 KPNA2 KRT15 KRT19 KRT20 KRT31 KRT38 KRT40 KRT79 LENG1 LINC00526 MAGEB4 MCM7 MCRS1 MED28 MED4 MOS MRPS23 MXI1 NCAPH2 NDC80 NDE1 NECAB2 NEFL NOC4L PARVG PMF1 PPP1R7 PPP2R5D PRC1 PRKAA2 RASAL2 RECK RIBC2 RNF20 SEC14L4 SERTAD3 SH2D4A SMARCD1 SMARCE1 STX11 SYNJ2BP THADA THOC1 TRIM54 TSG101 TUBGCP4 TXLNA TXLNB UBE2W UBXN11 USH1C VPS28 ZFYVE26 ZNF483 ZNF688 ZNF765 ZNRF2P1
Entrez ID		7251	83878
HPRD ID		03229	18276
Ensembl ID		ENSG00000074319	ENSG00000130307
Uniprot IDs		Q99816	A0A024R7H3 B4DUE8 G8JLM4 Q8N6Y0 Q8N8Y1
PDB IDs		1KPP 1KPQ 1M4P 1M4Q 1S1Q 2F0R 3IV1 3OBQ 3OBS 3OBU 3OBX 3P9G 3P9H 4EJE 4YC1 4ZNY 5VKG
Enriched GO Terms of Interacting Partners?
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