KEL and TUBA1A

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		KEL	TUBA1A
Description		Kell metallo-endopeptidase (Kell blood group)	tubulin alpha 1a
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nucleoplasm Cytosol Plasma Membrane Integral Component Of Membrane	Nucleus Cytoplasm Cytosol Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Neuromuscular Junction Cytoplasmic Ribonucleoprotein Granule Myelin Sheath Membrane Raft Recycling Endosome Extracellular Exosome
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metal Ion Binding	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Protein Domain Specific Binding
	Biological Process	Proteolysis Cellular Calcium Ion Homeostasis Regulation Of Cell Size Cellular Magnesium Ion Homeostasis Regulation Of Axon Diameter Vasoconstriction Myelination Skeletal Muscle Fiber Development Negative Regulation Of Potassium Ion Transmembrane Transport	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Cytoskeleton-dependent Intracellular Transport Regulation Of Synapse Organization Cell Division Ciliary Basal Body-plasma Membrane Docking
Pathways		Peptide ligand-binding receptors	Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Anchoring of the basal body to the plasma membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs		Phosphoramidon	Albendazole Vinblastine Mebendazole Epothilone D Patupilone CYT997 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE Artenimol Phenethyl Isothiocyanate
Diseases			Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS		Alcoholic chronic pancreatitis ( 28754779) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252)	Composite immunoglobulin trait (IgG/IgM) ( 28628107)
Interacting Genes		9 interacting genes: AGPS EDN1 EDN2 EDN3 EMC1 EWSR1 TUBA1A UBC XK	61 interacting genes: ANXA7 ARL3 ATXN3 B4GALT1 BTG1 C8orf33 CDKN1A CDKN2A CEP20 CLIP1 CNP CPEB2 CXCR1 CYLD DAG1 DUSP23 EGFR EML1 GEMIN7 GRM7 GSK3B GZMB HDAC6 HTRA2 KEL KPNB1 LRRK2 MAP2 MAP7D3 MAPK6 MAPRE1 MAX MX1 MYC NFATC1 NUDT3 PAFAH1B1 PLA2G7 S100A8 S100A9 SDC3 SIAH1 SMN1 SNCA SOCS6 SOCS7 SPART STARD13 STK11 SYK TAOK2 TIMM17A TK1 TLN1 TTR TUBB UBE2D3 VAV1 VCL YWHAQ ZAP70
Entrez ID		3792	7846
HPRD ID		00194	03959
Ensembl ID		ENSG00000197993	ENSG00000167552
Uniprot IDs		A0A077QP03 P23276	Q71U36
PDB IDs			5JCO 6J8F
Enriched GO Terms of Interacting Partners?
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