CENPS and HOMEZ

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CENPS	HOMEZ
Description		centromere protein S	homeobox and leucine zipper encoding
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GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex FANCM-MHF Complex	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	DNA Binding Chromatin Binding Double-stranded DNA Binding Protein Binding Protein Heterodimerization Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process	Resolution Of Meiotic Recombination Intermediates DNA Repair Cellular Response To DNA Damage Stimulus Replication Fork Processing Positive Regulation Of Protein Ubiquitination CENP-A Containing Nucleosome Assembly Interstrand Cross-link Repair Cell Division Kinetochore Assembly	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Fanconi Anemia Pathway Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Height ( 31562340) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		4 interacting genes: APP CENPM CENPX HOMEZ	37 interacting genes: AEN AXIN1 CENPS DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 ELOA GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK1 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPGR RPL9 SDCBP SH3RF2 SMARCB1 SMYD1 SNRPB2 SUMO2 TEAD4 TLE5 TRAF4 ZBTB7A ZNF688
Entrez ID		378708	57594
HPRD ID		18797	12167
Ensembl ID		ENSG00000175279	ENSG00000215271
Uniprot IDs		Q8N2Z9	Q8IX15
PDB IDs		4DRA 4DRB 4E44 4E45 4NDY 4NE1 4NE3 4NE5 4NE6	2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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