CCDC172 and DCTN2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC172	DCTN2
Description		coiled-coil domain containing 172	dynactin subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Sperm Midpiece	Kinetochore Cell Cytoplasm Centrosome Cytosol Dynactin Complex Microtubule Membrane Dynein Complex Growth Cone Vesicle Extracellular Exosome
	Molecular Function	Protein Binding	Motor Activity Protein Binding Protein Kinase Binding Spectrin Binding Identical Protein Binding
	Biological Process		G2/M Transition Of Mitotic Cell Cycle ER To Golgi Vesicle-mediated Transport Mitotic Spindle Organization Mitotic Metaphase Plate Congression Regulation Of G2/M Transition Of Mitotic Cell Cycle Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Transport Protein Localization To Centrosome Ciliary Basal Body-plasma Membrane Docking
Pathways			MHC class II antigen presentation Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic AURKA Activation by TPX2
Drugs
Diseases
GWAS		Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		14 interacting genes: DCTN2 FAM13C HDDC3 ISCU KDM1A NEFL PCM1 PLEKHF2 PSTPIP1 SH2D4A SMARCE1 TCHP TEAD4 TXNDC9	22 interacting genes: BICD1 BICD2 BLOC1S6 CALM1 CCDC172 DISC1 EGFR GADD45A GNAO1 GOLM1 GRB2 GSK3B HAUS1 HGS KIFC3 KPNA2 MAPK6 MAPRE3 MARCKSL1 PAFAH1B1 RPGR ZW10
Entrez ID		374355	10540
HPRD ID		18604	09568
Ensembl ID		ENSG00000182645	ENSG00000175203
Uniprot IDs		P0C7W6	A0A384MDU9 A8K8J9 B3KTX4 Q13561 V9HW58
PDB IDs
Enriched GO Terms of Interacting Partners?
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