DCTN2 and CCDC172

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DCTN2	CCDC172
Description		dynactin subunit 2	coiled-coil domain containing 172
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Cell Cytoplasm Centrosome Cytosol Dynactin Complex Microtubule Membrane Dynein Complex Growth Cone Vesicle Extracellular Exosome	Cytoplasm Sperm Midpiece
	Molecular Function	Motor Activity Protein Binding Protein Kinase Binding Spectrin Binding Identical Protein Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle ER To Golgi Vesicle-mediated Transport Mitotic Spindle Organization Mitotic Metaphase Plate Congression Regulation Of G2/M Transition Of Mitotic Cell Cycle Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Transport Protein Localization To Centrosome Ciliary Basal Body-plasma Membrane Docking
Pathways		MHC class II antigen presentation Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic AURKA Activation by TPX2
Drugs
Diseases
GWAS			Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		22 interacting genes: BICD1 BICD2 BLOC1S6 CALM1 CCDC172 DISC1 EGFR GADD45A GNAO1 GOLM1 GRB2 GSK3B HAUS1 HGS KIFC3 KPNA2 MAPK6 MAPRE3 MARCKSL1 PAFAH1B1 RPGR ZW10	14 interacting genes: DCTN2 FAM13C HDDC3 ISCU KDM1A NEFL PCM1 PLEKHF2 PSTPIP1 SH2D4A SMARCE1 TCHP TEAD4 TXNDC9
Entrez ID		10540	374355
HPRD ID		09568	18604
Ensembl ID		ENSG00000175203	ENSG00000182645
Uniprot IDs		A0A384MDU9 A8K8J9 B3KTX4 Q13561 V9HW58	P0C7W6
PDB IDs
Enriched GO Terms of Interacting Partners?
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