JUND and ACTR3

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		JUND	ACTR3
Description		JunD proto-oncogene, AP-1 transcription factor subunit	actin related protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nuclear Chromatin Nucleoplasm Transcription Factor Complex Protein-DNA Complex Transcription Factor AP-1 Complex	Cell Nucleus Cytoplasm Cytosol Arp2/3 Protein Complex Brush Border Cell-cell Junction Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Actin Cortical Patch Site Of Double-strand Break Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Transcription Factor Binding Nuclear Receptor Binding Enzyme Binding Transcription Regulatory Region DNA Binding	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Development Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Aging Circadian Rhythm Response To Radiation Response To Light Stimulus Response To Mechanical Stimulus Response To Organic Substance Response To Lipopolysaccharide Cellular Response To Hormone Stimulus Cellular Response To Stress Response To Cytokine Regulation Of Cell Proliferation Response To Drug Response To Peptide Hormone Positive Regulation Of Cell Differentiation Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To CAMP Regulation Of Cell Cycle Cellular Response To Calcium Ion	Establishment Or Maintenance Of Cell Polarity Asymmetric Cell Division Meiotic Chromosome Movement Towards Spindle Pole Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Spindle Localization Cilium Assembly Membrane Organization Actin Polymerization-dependent Cell Motility Cellular Response To Interferon-gamma
Pathways		Estrogen-dependent gene expression NGF-stimulated transcription	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Bronchodilator response in asthma ( 25562107) Estimated glomerular filtration rate ( 31015462 30604766) Hand grip strength ( 29691431) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 25673412) White blood cell count (monocyte) ( 28158719)	Metabolite levels ( 23823483) Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes		30 interacting genes: ACTR3 ATF3 BATF BCL6 BRCA1 CCND1 COP1 COPS5 DDIT3 EP300 ESR1 FOS FOSB FOSL2 HINFP JDP2 LINC00461 MAPK1 MAPK3 MAPK8 MAPK9 MDM2 MEN1 NFE2L1 NFE2L2 PPARG SLC25A12 SMAD3 SMAD4 TBP	16 interacting genes: ACTR2 ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CDH1 CTTN HCLS1 JUND SHARPIN UBE3A WASF1 WASF2 WASF3 WASL
Entrez ID		3727	10096
HPRD ID		01304	05024
Ensembl ID		ENSG00000130522	ENSG00000115091
Uniprot IDs		P17535	A0A024RAI1 B4DXW1 P61158
PDB IDs		3U86 5VPA 5VPB 5VPC 5VPD 5VPE 5VPF
Enriched GO Terms of Interacting Partners?
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