ILF2 and ERG

Number of citations of the paper that reports this interaction (PubMedID 24591637)
44

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ILF2	ERG
Description		interleukin enhancer binding factor 2	ETS transcription factor ERG
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Nucleolus Membrane Specific Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen Ribonucleoprotein Complex	Nuclear Chromatin Nucleus Cytoplasm Ribonucleoprotein Complex
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding ATP Binding Transferase Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding
	Biological Process	Transcription, DNA-templated Neutrophil Degranulation Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Signal Transduction Multicellular Organism Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Neutrophil degranulation
Drugs
Diseases			Ewing's sarcoma Prostate cancer
GWAS			Abdominal aortic aneurysm ( 27899403) Amyotrophic lateral sclerosis (sporadic) ( 24529757) B-cell acute lymphoblastic leukaemia ( 31767839) B-cell acute lymphoblastic leukaemia (high-hyperdiploidy) ( 31767839) Diastolic blood pressure ( 27841878 30578418) General cognitive ability ( 25383866) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549 28869591) Iron status biomarkers (iron levels) ( 28334935) Keratinocyte cancer (MTAG) ( 31174203) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Metabolite levels (HVA) ( 23319000) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244 27386562) Neonatal lupus ( 20662065) Non-response to antidepressants and depression ( 27622933) Platelet count ( 27863252) Plateletcrit ( 27863252) Pulse pressure ( 27841878 30578418) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)
Interacting Genes		11 interacting genes: CCNDBP1 DYNLT1 EEF1G EIF2AK2 EP300 ERG IL7R PRKDC SGSM2 SREK1 TRIM27	73 interacting genes: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HERC2 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 HUWE1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RING1 RNF2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SPOP STUB1 SYN1 TOP1 TOP2B TRIM25 TRIM33 TRIP12 UBR4 UBR5 UHRF1 USP9X XRN2
Entrez ID		3608	2078
HPRD ID		04419	01298
Ensembl ID		ENSG00000143621	ENSG00000157554
Uniprot IDs		B4DY09 F4ZW62 Q12905 Q53FG3	A0A0C4DG41 B4DN83 B4DVX5 B5MDW0 P11308
PDB IDs			1SXE 4IRG 4IRH 4IRI 5YBC 5YBD
Enriched GO Terms of Interacting Partners?
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