IGKC and IGHG1

Number of citations of the paper that reports this interaction (PubMedID 1522589)
6

Data Source:
HPRD (in vitro)

		IGKC	IGHG1
Description		immunoglobulin kappa constant	immunoglobulin heavy constant gamma 1 (G1m marker)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane External Side Of Plasma Membrane Immunoglobulin Complex Immunoglobulin Complex, Circulating Extracellular Exosome Blood Microparticle	Extracellular Region Extracellular Space External Side Of Plasma Membrane Immunoglobulin Complex, Circulating Extracellular Exosome Blood Microparticle
	Molecular Function	Antigen Binding Immunoglobulin Receptor Binding	Antigen Binding Protein Binding Immunoglobulin Receptor Binding
	Biological Process	Retina Homeostasis Immunoglobulin Production Receptor-mediated Endocytosis Phagocytosis, Recognition Phagocytosis, Engulfment Immune Response Complement Activation Complement Activation, Classical Pathway Regulation Of Complement Activation Fc-epsilon Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Defense Response To Bacterium Innate Immune Response Regulation Of Immune Response B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Activation Leukocyte Migration	Phagocytosis, Recognition Phagocytosis, Engulfment Complement Activation Complement Activation, Classical Pathway Cytokine-mediated Signaling Pathway Regulation Of Complement Activation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Defense Response To Bacterium Innate Immune Response B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Activation
Pathways
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) Composite immunoglobulin trait (IgG/IgM) ( 28628107) IgG levels ( 23225573)
Interacting Genes		4 interacting genes: CD40LG IGHG1 MLH1 SMARCD1	7 interacting genes: CD40LG FCGR3A FCGR3B IGKC SWAP70 TRIM21 UCHL5
Entrez ID		3514	3500
HPRD ID		00921	11755
Ensembl ID		ENSG00000211592	ENSG00000211896
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?
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