APOE and CYP2C8

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 33
  • Data Source:
  • BioGRID (two hybrid)

APOE

CYP2C8

Description apolipoprotein E cytochrome P450 family 2 subfamily C member 8
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood metabolite levels ( 24816252)
  • Gout ( 22179738)
  • Immune response to smallpox vaccine (IL-6) ( 22542470)
  • Osteonecrosis of the jaw ( 18594024)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Response to clopidogrel therapy ( 19706858)
  • Tuberculosis ( 24057671)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Warfarin maintenance dose ( 23755828)
Interacting Genes 55 interacting genes: A2M ALB ANKH APP ARFGAP1 CDC37 CNTF CSNK2A1 CTSB CYP2C18 CYP2C8 ECSIT ELAVL1 EPN2 FARSA FBXL12 FOXG1 FXYD7 GCDH HTRA1 IFIT3 IFIT5 IQSEC1 LCAT LDLR LONP1 LOXL4 LRP1 LRP2 LRP8 MAP2 MAPT MAST1 MID1IP1 NEFM NOS3 PCMT1 PDCD4 PLEKHA6 PLTP PRAM1 PRDX2 PRNP PSEN1 RHEB RNF32 RPL4 SCARB1 SORL1 ST13 TIMM29 TREM2 TYRO3 VLDLR ZNF558 12 interacting genes: A2M APOE BLMH DNAJB1 ECSIT EXOC6 IFIT3 LONP1 MAST1 PSEN1 RIN3 RNF32
Entrez ID 348 1558
HPRD ID 00135 03083
Ensembl ID ENSG00000130203 ENSG00000138115
Uniprot IDs A0A0S2Z3D5 P02649 B7Z1F5 P10632
PDB IDs 1B68 1BZ4 1EA8 1GS9 1H7I 1LE2 1LE4 1LPE 1NFN 1NFO 1OEF 1OEG 1OR2 1OR3 2KC3 2KNY 2L7B 6NCN 6NCO 1PQ2 2NNH 2NNI 2NNJ 2VN0
Enriched GO Terms of Interacting Partners?
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