IFNGR2 and ANXA5

Number of citations of the paper that reports this interaction (PubMedID 16670301)
6

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		IFNGR2	ANXA5
Description		interferon gamma receptor 2	annexin A5
Image
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane	Extracellular Region Intracellular Cytoplasm Cytosol Focal Adhesion External Side Of Plasma Membrane Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Endothelial Microparticle
	Molecular Function	Cytokine Receptor Activity Interferon-gamma Receptor Activity	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Response To Virus Cytokine-mediated Signaling Pathway Interferon-gamma-mediated Signaling Pathway Regulation Of Interferon-gamma-mediated Signaling Pathway	Platelet Degranulation Signal Transduction Blood Coagulation Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Calcium Ion Transmembrane Transport
Pathways		Interferon gamma signaling Regulation of IFNG signaling Regulation of IFNG signaling	Platelet degranulation
Drugs		Interferon gamma-1b	L-Alpha-Glycerophosphorylserine L-thioproline K201 L-Alpha-Glycerophosphorylethanolamine 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid N,O6-Disulfo-Glucosamine 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid Copper
Diseases		Tuberculosis IFN-gamma/IL-12 axis, including the following five diseases: IL-12 p40 subunit deficiency; IL-12 receptor (IL-12R) beta1 chain deficiency; IFN-gamma receptor (IFN gamma R) alpha chain deficiency; IFN-gamma receptor (IFN gamma R) beta chain deficiency; STAT-1 deficiency
GWAS		Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908 22936669 23128233) Diverticular disease ( 30177863) Educational attainment ( 25201988) Inflammatory bowel disease ( 28067908) Multiple sclerosis ( 31604244 24076602) Obesity-related traits ( 23251661) Psoriasis ( 25854761) Rheumatoid arthritis ( 30423114 24390342)	Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Resting-state electroencephalogram vigilance ( 29703947)
Interacting Genes		8 interacting genes: ANXA5 CAMK2D DNAJA3 IFNG IFNGR1 JAK2 NR3C1 RPL37A	17 interacting genes: ACTG1 APP COL10A1 COL2A1 EED EIF4G1 FDFT1 IFNGR2 ITGB5 KDR LAMC3 PPP2R1B SUPT4H1 TERF1 TERF2 TERF2IP TINF2
Entrez ID		3460	308
HPRD ID		00956	00568
Ensembl ID		ENSG00000159128	ENSG00000164111
Uniprot IDs		A8K881 E7EUY1 P38484	P08758 V9HWE0
PDB IDs		5EH1 6E3K 6E3L	1ANW 1ANX 1AVH 1AVR 1HAK 1HVD 1HVE 1HVF 1HVG 1SAV 2XO2 2XO3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?