APOBEC1 and SYNCRIP

Number of citations of the paper that reports this interaction (PubMedID 11352648)
12

Data Source:
BioGRID (pull down)

		APOBEC1	SYNCRIP
Description		apolipoprotein B mRNA editing enzyme catalytic subunit 1	synaptotagmin binding cytoplasmic RNA interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Cytidine Deaminase Activity Cytosine Deaminase Activity Protein Binding Enzyme Activator Activity Zinc Ion Binding Protein Domain Specific Binding MRNA 3'-UTR AU-rich Region Binding Ribonucleoprotein Complex Binding	RNA Binding MRNA Binding Protein Binding Poly(A) Binding MRNA 5'-UTR Binding
	Biological Process	RNA Processing MRNA Processing Lipid Metabolic Process Triglyceride Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Response To Gamma Radiation Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Regulation Of Cell Proliferation Lipoprotein Biosynthetic Process Lipoprotein Transport Positive Regulation Of Catalytic Activity Response To Ethanol MRNA Stabilization Response To Calcium Ion Defense Response To Virus DNA Cytosine Deamination DNA Demethylation Negative Regulation Of Triglyceride Metabolic Process Negative Regulation Of Methylation-dependent Chromatin Silencing Positive Regulation Of MRNA Modification	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Viral Process Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Body mass index ( 28552196) Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899)
Interacting Genes		8 interacting genes: A1CF APOBEC2 BAG4 CELF2 DNAJB11 DND1 KPNA2 SYNCRIP	31 interacting genes: A1CF APOBEC1 APP CSDE1 EPRS1 ESR1 GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 NUPR1 PABPC1 PCSK7 PLCG1 PRMT1 PTPN11 SMN1 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9
Entrez ID		339	10492
HPRD ID		02531	06734
Ensembl ID		ENSG00000111701	ENSG00000135316
Uniprot IDs		P41238	B7Z645 O60506 Q59GL1
PDB IDs			2DGU 2MXT 2NBB
Enriched GO Terms of Interacting Partners?
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