ICAM3 and CD209

Number of citations of the paper that reports this interaction (PubMedID 10721994)
385

Data Source:
HPRD (in vitro, in vivo)

		ICAM3	CD209
Description		intercellular adhesion molecule 3	CD209 molecule
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Host Cell
	Molecular Function	Signaling Receptor Binding Integrin Binding Protein Binding	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding Peptide Antigen Binding Virion Binding Metal Ion Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Phagocytosis Cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response Cell-cell Adhesion	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Morphology Or Physiology Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation Regulation Of T Cell Proliferation Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus B Cell Adhesion
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling	CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)	Blood protein levels ( 30072576 29875488)
Interacting Genes		11 interacting genes: APP CD209 CLEC4M EZR GCC2 ITGAD ITGAL ITGB2 MSN PRKCQ ZBTB16	7 interacting genes: CEACAM1 CLEC4M CLU ICAM2 ICAM3 ITGAM VAC14
Entrez ID		3385	30835
HPRD ID		00889	05241
Ensembl ID		ENSG00000076662	ENSG00000090659
Uniprot IDs		A0A024R7C1 K7ERN2 P32942	B2R907 B4E2A8 M0R0P0 Q9NNX6 X6RB12
PDB IDs		1T0P	1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV
Enriched GO Terms of Interacting Partners?
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