CD209 and VAC14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CD209	VAC14
Description		CD209 molecule	VAC14 component of PIKFYVE complex
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Host Cell	Golgi Membrane Extrinsic Component Of Vacuolar Membrane Vacuolar Membrane Endoplasmic Reticulum Cytosol Endosome Membrane Early Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle PAS Complex
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding Peptide Antigen Binding Virion Binding Metal Ion Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Morphology Or Physiology Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation Regulation Of T Cell Proliferation Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus B Cell Adhesion	Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Positive Regulation Of Kinase Activity
Pathways		CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions	Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pulse pressure ( 28135244)
Interacting Genes		7 interacting genes: CEACAM1 CLEC4M CLU ICAM2 ICAM3 ITGAM VAC14	53 interacting genes: ACSS1 APP ASB13 BCL2L1 BHLHE40 C11orf54 C4orf33 CASP1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 CRK DDAH2 FNDC3B GALT GINS3 HNRNPLL JMJD7 KRTAP19-5 KRTAP19-7 KYAT1 LINC00518 LPAL2 MGAT5B MPPED2 MTMR9 MVP NGB NOS1 NTAQ1 PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PRADC1 PRR13 PRR20A RBFOX2 RHOXF2 SIGLEC5 SMUG1 SNF8 SPRYD7 SRPK2 TCEANC TP53BP1 ZCWPW1 ZNF34
Entrez ID		30835	55697
HPRD ID		05241	07660
Ensembl ID		ENSG00000090659	ENSG00000103043
Uniprot IDs		B2R907 B4E2A8 M0R0P0 Q9NNX6 X6RB12	Q08AM6
PDB IDs		1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV
Enriched GO Terms of Interacting Partners?
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