XIAP and INPP5D

  • Number of citations of the paper that reports this interaction (PubMedID 22815893)
  • 12
  • Data Source:
  • BioGRID (two hybrid)

XIAP

INPP5D

Description X-linked inhibitor of apoptosis inositol polyphosphate-5-phosphatase D
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Alzheimer's disease (late onset) ( 30617256 24162737)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Contrast sensitivity ( 24152035)
  • Crohn's disease ( 22412388 23128233)
  • Eosinophil counts ( 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Family history of Alzheimer's disease ( 30617256)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Perceived unattractiveness to mosquitoes ( 28199695)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Sum eosinophil basophil counts ( 27863252)
Interacting Genes 82 interacting genes: ACVRL1 AFP AIFM1 AKT1 AKT2 BCL2 BIRC5 BRCA1 CASP10 CASP3 CASP7 CASP9 CCNB1 CDC42 CDK1 CHEK1 CKS1B COMMD1 DIABLO DNM2 DTX3 DYNLL2 ELAVL1 ERCC3 FAF1 GOLGA2 GSK3B GSPT1 HNRNPA1 HSPA1A HTRA1 HTRA2 IKBKE INPP5D KCNJ6 LONRF1 MAGED1 MAP3K2 MAP3K3 MAP3K7 MDM2 NEK6 NOD1 NOD2 NOTCH1 NTAQ1 PPIH RAF1 RFC5 RIPK2 RIPK3 RIPK4 SEPTIN4 SERTAD1 SQSTM1 SSX2IP STRADB STUB1 TAB1 TAB2 TBK1 TGFBR1 TLE3 TRAF6 TRIM32 TRIM8 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2I UBE2J2 UBE2N UBE2V1 UBE2V2 UBE2W VPS37C XAF1 42 interacting genes: ARAP1 CD22 CD300LF CRKL CSF1R CSF3R DAB1 DAB2 DOK1 DOK2 DOK3 EPOR FCGR1B FCGR2B FGR FLT3 GAB1 GAB2 GRB2 HCK IL4R JAK1 JAK3 KHDRBS3 KIT KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 LILRB4 LYN MET NOTCH2NLA PECAM1 PLCG1 PTPN11 SH3KBP1 SHC1 SLAMF1 XIAP ZDHHC17
Entrez ID 331 3635
HPRD ID 02094 09033
Ensembl ID ENSG00000101966 ENSG00000168918
Uniprot IDs B2R9R2 P98170 Q92835
PDB IDs 1C9Q 1F9X 1G3F 1G73 1I3O 1I4O 1I51 1KMC 1NW9 1TFQ 1TFT 2ECG 2JK7 2KNA 2OPY 2OPZ 2POI 2POP 2QRA 2VSL 3CLX 3CM2 3CM7 3EYL 3G76 3HL5 3UW4 3UW5 4EC4 4HY0 4IC2 4IC3 4J3Y 4J44 4J45 4J46 4J47 4J48 4KJU 4KJV 4KMP 4MTZ 4OXC 4WVS 4WVT 4WVU 5C0K 5C0L 5C3H 5C3K 5C7A 5C7B 5C7C 5C7D 5C83 5C84 5M6E 5M6F 5M6H 5M6L 5M6M 5O6T 5OQW 6EY2 6GJW 6QCI 2YSX 6IBD
Enriched GO Terms of Interacting Partners?
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