HES1 and HMGCL

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 114
  • Data Source:
  • BioGRID (two hybrid)

HES1

HMGCL

Description hes family bHLH transcription factor 1 3-hydroxy-3-methylglutaryl-CoA lyase
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcoholic chronic pancreatitis ( 28754779)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)
  • Thyroid stimulating hormone levels ( 30367059)
  • High light scatter reticulocyte count ( 27863252)
  • Immature fraction of reticulocytes ( 27863252)
  • Reticulocyte fraction of red cells ( 27863252)
Interacting Genes 35 interacting genes: APCS APH1A ASGR2 CSNK1E FANCA FANCE FANCF FANCG FANCL FHL1 FOXG1 GAPDH HDAC6 HES6 HEY1 HEY2 HMGB1 HMGCL ID1 ID2 ID3 ID4 JAK2 LTBR NHLH2 NR4A1 NUDT3 PRKCA PTK2 SIRT1 STAT3 TLE1 TLE2 UBQLN1 YWHAB 9 interacting genes: ADAMTS10 ARL6IP1 DNAJA1 GTF2B HES1 HSD17B10 MS4A7 PEX5 RNF126
Entrez ID 3280 3155
HPRD ID 00770 02003
Ensembl ID ENSG00000114315 ENSG00000117305
Uniprot IDs Q14469 P35914
PDB IDs 2MH3 2CW6 3MP3 3MP4 3MP5
Enriched GO Terms of Interacting Partners?
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