HPX and GLUD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HPX	GLUD1
Description		hemopexin	glutamate dehydrogenase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Collagen-containing Extracellular Matrix Extracellular Exosome Endocytic Vesicle Lumen Blood Microparticle	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Heme Transporter Activity Metal Ion Binding	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Cellular Iron Ion Homeostasis Receptor-mediated Endocytosis Heme Transport Viral Process Hemoglobin Metabolic Process Heme Metabolic Process Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Interferon-gamma-mediated Signaling Pathway	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Oxidation-reduction Process Tricarboxylic Acid Metabolic Process
Pathways		Scavenging of heme from plasma	Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism
Drugs			Glutamic Acid NADH Hexachlorophene Guanosine-5'-Triphosphate Aluminum chloride
Diseases
GWAS		Blood protein levels ( 29875488)
Interacting Genes		2 interacting genes: GLUD1 TP63	12 interacting genes: ASGR2 CRP DYNLL1 GOT2 HPX HSD17B10 LSM1 NR4A1 ORM1 SEC62 STAT5A VTN
Entrez ID		3263	2746
HPRD ID		00793	11748
Ensembl ID		ENSG00000110169	ENSG00000148672
Uniprot IDs		P02790 Q9BS19	E9KL48 P00367
PDB IDs			1L1F 1NR1 6DQG
Enriched GO Terms of Interacting Partners?
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