HOXC13 and RHOXF2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		HOXC13	RHOXF2
Description		homeobox C13	Rhox homeobox family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Nuclear Chromatin Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Sequence-specific DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding
	Biological Process	Hair Follicle Development Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Nail Development Tongue Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Biliary atresia ( 20460270) Blond vs. brown/black hair color ( 30531825) Hair shape ( 29220522) Toenail selenium levels ( 25343990) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		7 interacting genes: APEX1 ELF1 HNRNPAB HOXC9 MEIS1 NR2E3 RHOXF2	58 interacting genes: ARID5A ARMCX2 ATN1 ATXN1 CCDC33 CCNK CHAC1 CLASRP CLDN7 CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FBF1 HNRNPLL HOXC13 KRTAP19-5 KRTAP19-7 LASP1 LENG8 LSM4 LZTS2 MAGED1 MED7 MVP NANOG NEU4 PITX1 PLOD3 POLR3D POU2AF1 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS SERF2 SNAPC1 SUMO1 TENT5B TENT5C TENT5D TLE5 TMCC2 TOLLIP TRIP13 UBE2I UPF1 UTP6 VAC14 VPS25 ZBTB32
Entrez ID		3229	84528
HPRD ID		00862	02345
Ensembl ID		ENSG00000123364	ENSG00000131721
Uniprot IDs		P31276	Q9BQY4
PDB IDs
Enriched GO Terms of Interacting Partners?
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