HNRNPK and CCAR1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		HNRNPK	CCAR1
Description		heterogeneous nuclear ribonucleoprotein K	cell division cycle and apoptosis regulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Podosome Nucleus Nucleoplasm Cytoplasm Focal Adhesion Cytoplasmic Stress Granule Membrane Cell Projection Extracellular Exosome Catalytic Step 2 Spliceosome	Nucleus Nuclear Envelope Lumen Nucleoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding Cadherin Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing Signal Transduction Regulation Of Low-density Lipoprotein Particle Clearance Viral Process RNA Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Positive Regulation Of Cell Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA HCMV Late Events	mRNA Splicing - Major Pathway
Drugs		Artenimol Phenethyl Isothiocyanate
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Cannabis dependence symptom count ( 27028160)
Interacting Genes		115 interacting genes: ABI2 APBB1 AQP5 AURKA BTRC C6orf226 CBLB CCAR1 CCDC33 CDKN1A CEBPB CIRBP CMTM5 CNNM3 CSK CTNNBL1 DALRD3 DDX1 DDX17 DDX5 DHX9 DIDO1 DOCK2 EIF3F ELAVL1 FBXL18 FBXO7 FBXW7 FYN GFI1B GRAP2 GRB2 GZMA GZMK H3-4 HCK HMGB1 HNRNPA0 HNRNPD HNRNPL HNRNPLL ITK ITSN2 KHDRBS1 KHDRBS2 KHDRBS3 LYN MAPK10 MARK4 MATR3 MDM2 NCK2 NEDD4 NPDC1 PABPC1 PCBP1 PCBP2 PCDHB14 PCGF3 PELI2 PIN1 PPP1R10 PRKCD PRMT1 PRPF31 PRPF40A PRR3 QKI RALY RASD1 RBFOX2 RBM10 RBM14 RBM3 RBM4 RBM41 RBM42 RBM7 RBMX RBMY1A1 RBMY1F RNA18SN5 RNA28SN5 RTP5 SAFB SF1 SMAD3 SNRPA SORBS3 SPG7 SRC SREK1 SRPK2 SRRT SRSF3 SUMO1 SUMO2 SYNCRIP TBP TCERG1 TERF2IP TYK2 U2AF1 UBE2I VAV1 WBP4 WWOX YBX1 YTHDC1 YWHAQ ZFC3H1 ZNF385C ZNF688 ZNF792 ZNRF2P1	11 interacting genes: CASP10 CHERP DNAAF6 GOLGA2 HMGB1 HNRNPK MDM2 RBM10 RNF113A SFN U2AF2
Entrez ID		3190	55749
HPRD ID		02834	10811
Ensembl ID		ENSG00000165119	ENSG00000060339
Uniprot IDs		B4DUQ1 P61978	Q8IX12
PDB IDs		1J5K 1KHM 1ZZI 1ZZJ 1ZZK
Enriched GO Terms of Interacting Partners?
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