HNRNPA1 and PRMT3

Number of citations of the paper that reports this interaction (PubMedID 19101556)
5

Data Source:
BioGRID (pull down)

		HNRNPA1	PRMT3
Description		heterogeneous nuclear ribonucleoprotein A1	protein arginine methyltransferase 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	Single-stranded DNA Binding RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding MiRNA Binding Pre-mRNA Binding Telomeric Repeat-containing RNA Binding G-rich Strand Telomeric DNA Binding	Nucleic Acid Binding Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Ribosome Binding Metal Ion Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus Fibroblast Growth Factor Receptor Signaling Pathway Viral Process RNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Glucose Starvation MRNA Transport Nuclear Export Import Into Nucleus Regulation Of RNA Metabolic Process Cellular Response To Sodium Arsenite	Protein Methylation Negative Regulation Of Protein Ubiquitination Peptidyl-arginine N-methylation
Pathways		FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	RMTs methylate histone arginines Protein methylation
Drugs			S-adenosyl-L-homocysteine
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Carotid intima media thickness (maximum) ( 31801372) Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906) Pursuit maintenance gain ( 29064472) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		40 interacting genes: ABHD16A APP BCL2L1 CLK1 ERG ESR1 FEN1 H3-4 H3C1 HIPK3 HMGA1 HNRNPH3 KHSRP NFKBIA NR0B2 NR3C1 PABPN1 PHYHIP PPIL1 PRKDC PRMT1 PRMT2 PRMT3 PRRC2A RNF14 RPL21 RPS6KB2 SAFB SNRNP200 SREK1 SRPK1 SRPK2 SUFU TFEC TNPO1 TRA2B TRAF6 TTF2 XIAP XRN1	8 interacting genes: FBL HNRNPA1 PABPN1 PPARD RASSF2 RPS2 STAT1 TSC22D2
Entrez ID		3178	10196
HPRD ID		01242	11934
Ensembl ID		ENSG00000135486	ENSG00000185238
Uniprot IDs		A0A024RAZ7 A0A024RB53 P09651	O60678 Q8WUV3
PDB IDs		1HA1 1L3K 1PGZ 1PO6 1U1K 1U1L 1U1M 1U1N 1U1O 1U1P 1U1Q 1U1R 1UP1 2H4M 2LYV 2UP1 4YOE 5MPG 5MPL 5ZGD 5ZGL 6BXX 6DCL 6J60	2FYT 3SMQ 4HSG 4QQN 4RYL
Enriched GO Terms of Interacting Partners?
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