HGD and GIT2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

		HGD	GIT2
Description		homogentisate 1,2-dioxygenase	GIT ArfGAP 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Nucleoplasm Focal Adhesion
	Molecular Function	Homogentisate 1,2-dioxygenase Activity Protein Binding Identical Protein Binding Metal Ion Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Cellular Amino Acid Metabolic Process L-phenylalanine Catabolic Process Tyrosine Catabolic Process Oxidation-reduction Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		Tyrosine catabolism
Drugs
Diseases		Alkaptonuria
GWAS			Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		4 interacting genes: CLDN7 GIT2 PCDHGC3 TERF1	44 interacting genes: ACTG1 ACTN1 ARHGEF7 ATF5 C4BPA CALCOCO2 CORO1A E2F2 EDC4 GCH1 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		3081	9815
HPRD ID		06315	09779
Ensembl ID		ENSG00000113924	ENSG00000139436
Uniprot IDs		B3KW64 Q93099	F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58
PDB IDs		1EY2 1EYB
Enriched GO Terms of Interacting Partners?
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